Results 11 to 20 of about 16,430 (217)
Misconceptions about paraoxonase-1
Brazilian Journal of Otorhinolaryngology, 2022 Michael Mackness, Eser Y. Sozmen
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Paraoxonase 1 Activity and Survival in Sepsis Patients
Balkan Medical Journal, 2015 Background: Sepsis is a state of augmented oxidative stress and diminished antioxidant capacity. High density lipoprotein (HDL) particles were shown to possess antioxidant and anti-inflammatory properties, as well as Paraoxonase 1 (PON1), which is an ...
Volkan İnal +4 more
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Dietary cholesterol increases paraoxonase 1 enzyme activity [PDF]
Journal of Lipid Research, 2012 HDL-associated paraoxonase 1 (PON1) activity has been consistently associated with cardiovascular and other diseases. Vitamins C and E intake have previously been positively associated with PON1 in a subset of the Carotid Lesion Epidemiology and Risk ...
Daniel S. Kim +10 more
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Paraoxonase-1 and Early-Life Environmental Exposures
Annals of Global Health, 2016 Acute and chronic exposures to widely used organophosphorus (OP) insecticides are common. Children's detoxification mechanisms are not well developed until several years after birth.
Judit Marsillach +2 more
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Paraoxonase 1 polymorphisms and survival [PDF]
European Journal of Human Genetics, 2004 The antioxidant enzyme paraoxonase 1 (PON1) has previously been suggested to confer protection against coronary heart disease (CHD), one of the main causes of death in the Western world. Two coding polymorphisms, 55M/L and 192Q/R, and a promoter variant, -107C/T, has been extensively studied with respect to susceptibility to CHD. In this study, we have
Christiansen, Lene +3 more
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Paraoxonase 1 in neurological disorders [PDF]
Redox Report, 2013 Paroxonase 1 displays multiple physiological activities that position it as a putative player in the pathogenesis of neurological disorders. Here we reviewed the literature focusing on the role of paraoxonase 1 (PON1) as a factor in the risk of stroke and the major neurodegenerative diseases.
Teresita, Menini, Alejandro, Gugliucci
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Haplotype-Phenotype Relationships of Paraoxonase-1 [PDF]
Cancer Epidemiology, Biomarkers & Prevention, 2005 Abstract Paraoxonase 1 (PON1) is an enzyme with multiple activities, including detoxification of organophosphates. It is believed to be important in preventing neurotoxic damage and has also been implicated in atherosclerosis. The PON1 gene contains five common polymorphisms, three in the promoter (−909G > C, −162A > G ...
Jia, Chen +4 more
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Paraoxonase 1 in Chronic Kidney Failure [PDF]
Journal of Lipids, 2012 In this review we summarize the findings from the literature and our own laboratory on the decreased PON1 activity in renal failure, the mechanisms proposed and the effect of interventions. In addition to profound alterations in lipoproteins, reduced serum PON1 activity has been clearly established in the past decade and could contribute to accelerated
Alejandro Gugliucci +2 more
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Solubilization and Humanization of Paraoxonase-1 [PDF]
Journal of Lipids, 2012 Paraoxonase-1 (PON1) is a serum protein, the activity of which is related to susceptibility to cardiovascular disease and intoxication by organophosphorus (OP) compounds. It may also be involved in innate immunity, and it is a possible lead molecule in the development of a catalytic bioscavenger of OP pesticides and nerve agents.
Mohosin Sarkar +8 more
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The Effects of Bioavailability-Enhanced Curcuminoids on Serum Paraoxonase-1 Activity in Patients with Metabolic Syndrome [PDF]
Journal of Cardio-Thoracic Medicine, 2021 Introduction: Metabolic syndrome (MetS) is characterised by a clustering of metabolic cardiovascular disease (CVD) risk factors that include: central obesity, impaired glucose metabolism, dyslipidaemia (hypertriglyceridemia, increased low-density ...
Atena Raee +7 more
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