Results 11 to 20 of about 27,544,016 (212)
Paraoxonase 1 Activity and Survival in Sepsis Patients
Balkan Medical Journal, 2015 Background: Sepsis is a state of augmented oxidative stress and diminished antioxidant capacity. High density lipoprotein (HDL) particles were shown to possess antioxidant and anti-inflammatory properties, as well as Paraoxonase 1 (PON1), which is an ...
Volkan İnal +4 more
doaj +6 more sources
Misconceptions about paraoxonase-1
Brazilian Journal of Otorhinolaryngology, 2022 Michael Mackness, Eser Y. Sozmen
doaj +4 more sources
Genetic polymorphisms of paraoxonase 1 and susceptibility to atherogenesis [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2013 Introduction. Paraoxonase 1 (PON1) is a multifunctional enzyme associated with high-density lipoprotein particles (HDL). It is a cellular antioxidant that hydrolyses oxidized macromolecules, especially low-density lipoproteins (ox-LDL).
Grubiša Ivana +5 more
doaj +4 more sources
Paraoxonase-1 and Early-Life Environmental Exposures
Annals of Global Health, 2016 Acute and chronic exposures to widely used organophosphorus (OP) insecticides are common. Children's detoxification mechanisms are not well developed until several years after birth.
Judit Marsillach +2 more
doaj +5 more sources
Paraoxonase-1 and clopidogrel efficacy [PDF]
Nature Medicine, 2011 Clopidogrel active thiol metabolite is formed through 1) a cytochrome P450 (CYP dependent oxidation to a thiolactone : 2-oxoclopidogrel. Then a second CYP dependent oxidation to a sulfenic acid which is reduced by excess glutathione to the active cis -thiol-acid.
Thomas, Cuisset +5 more
+10 more sources
Paraoxonase 1 and Chronic Kidney Disease: A Meta-Analysis
Journal of Clinical Medicine, 2023 Oxidative stress is known to be associated with the pathophysiology of chronic kidney disease (CKD). Paraoxonase 1 (PON1) is an antioxidant enzyme that has been proposed as a biomarker for CKD.
J. Watanabe +2 more
semanticscholar +1 more source
The Iraqi Journal of Medical Sciences, 2022 Background: The use of labor induction to shorten the duration of a pregnancy has increased steadily during the last few decades. Paraoxonase 1 levels were observed to be higher in the oxytocin-induced group than in the spontaneous labor group ...
Sarah N. Ahmed, Ayla K. Ghalib
doaj +6 more sources
Paraoxonase 1 gene polymorphisms in lipid oxidation and atherosclerosis development
Frontiers in Genetics, 2022 Paraoxonase 1 (PON1) is calcium-dependent aryldialkylphosphatase, thought to possess; anti-oxidant, anti-adhesion, anti-inflammatory, anti-thrombosis and anti-apoptosis effects, as well as lipid-modifying properties.
Marija M Vavlukis +3 more
semanticscholar +1 more source
Neuroscience and Biobehavioral Reviews, 2021 Lowered high-density lipoprotein (HDL) cholesterol has been reported in major depressive disorder, bipolar disorder, first episode of psychosis, and schizophrenia.
G. Morris, B. Puri, Michael Maes
semanticscholar +1 more source
Paraoxonase 1 polymorphisms and survival [PDF]
European Journal of Human Genetics, 2004 The antioxidant enzyme paraoxonase 1 (PON1) has previously been suggested to confer protection against coronary heart disease (CHD), one of the main causes of death in the Western world. Two coding polymorphisms, 55M/L and 192Q/R, and a promoter variant, -107C/T, has been extensively studied with respect to susceptibility to CHD. In this study, we have
Christiansen, Lene +3 more
openaire +2 more sources