Results 71 to 80 of about 16,132 (204)
Pharmacogenetics of paraoxonases: a brief review [PDF]
The human paraoxonase (PON) gene family consists of three members, PON1, PON2, and PON3, aligned next to each other on chromosome 7. By far the most-studied member of the family is the serum paraoxonase 1 (PON1), a high-density lipoprotein-associated esterase/lactonase.
Draganov, D. I., La Du, Bert N.
openaire +3 more sources
Background and Objective: Paraoxonase-1 is an important factor in preventing lipid oxidation and formation of oxidized low-density lipoprotein. There are conflicting reports on the impact of physical activity on serum level of Paraoxonase-1.
Amouzad Mahdirejei T +3 more
doaj
Sepsis in Dogs and Cats—Consensus Definition and Clinical Criteria
ABSTRACT Sepsis is the clinical syndrome that results from the host response to severe or widespread infection and is a frequent cause of death in veterinary critical care settings. Rapid diagnosis aids early treatment initiation, and hence, how sepsis is defined and identified clinically has implications for patient outcomes.
Robert Goggs +13 more
wiley +1 more source
The paraoxonase gene family contains at least three members, including PON1, PON2 and PON3, which are located on chromosome 7q21.3-22.1. Until recently, there has been little insight into the role of the respective gene products in human physiology and pathology.
openaire +2 more sources
Analysis of structural and functional parameters of HDL has gained significant momentum in recent years because they are stronger predictors of cardiovascular risk than HDL-cholesterol levels. Surprisingly, in most HDL studies, very low attention is paid
Michael Holzer +4 more
doaj +1 more source
Abstract Objective To compare the systemic inflammatory and oxidative stress responses after elective ovariectomy via open surgery (OPEN) or laparoscopy (LAP) in anestrus bitches. Study design Prospective, blinded, randomized clinical trial. Animals A total of 26 healthy bitches.
Alfonso Calabria +10 more
wiley +1 more source
Paraoxonase 1 phenotype and paraoxonase activity in asthmatic patients.
Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics. PON1 activity varies widely among individuals and ethnic groups, partly related to polymorphisms.
GENÇER, NAHİT +4 more
openaire +5 more sources
The CHG index, derived from total cholesterol, high‐density lipoprotein, and fasting blood glucose, was associated with 90‐day functional outcomes after acute ischemic stroke. ABSTRACT Background: Acute ischemic stroke (AIS) is a major cause of global disability and mortality.
Xinyue Yuan +5 more
wiley +1 more source
Antioxidant Status and Serum Prolidase Activity in Women with Subclinical Hypothroidism
Purpose: Thyroid hormones are associated with the oxidant-antioxidant balance in the organism. Hypothyroidism is associated with impaired collagen turnover. We aimed to evaluate paraoxonase (PON) and arylesterase (ARE) activities, which prevent oxidative
Mehmet Ali Eren +6 more
doaj +1 more source
High density lipoprotein (HDL)-associated paraoxonase (PON) seems to play a major role in the protection of low density lipoprotein (LDL) against peroxidation by HDL, and the partly purified enzyme exerts a dose-dependent protective effect.
Huibi Cao +3 more
doaj +1 more source

