Results 71 to 80 of about 16,132 (204)

Pharmacogenetics of paraoxonases: a brief review [PDF]

open access: yesNaunyn-Schmiedeberg's Archives of Pharmacology, 2004
The human paraoxonase (PON) gene family consists of three members, PON1, PON2, and PON3, aligned next to each other on chromosome 7. By far the most-studied member of the family is the serum paraoxonase 1 (PON1), a high-density lipoprotein-associated esterase/lactonase.
Draganov, D. I., La Du, Bert N.
openaire   +3 more sources

Effect of four weeks of endurance training on serum level of paraoxonase-1 and lipid profile in non-athlete obese men

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: Paraoxonase-1 is an important factor in preventing lipid oxidation and formation of oxidized low-density lipoprotein. There are conflicting reports on the impact of physical activity on serum level of Paraoxonase-1.
Amouzad Mahdirejei T   +3 more
doaj  

Sepsis in Dogs and Cats—Consensus Definition and Clinical Criteria

open access: yesJournal of Veterinary Emergency and Critical Care, Volume 36, Issue 4, Page 445-469, July/August 2026.
ABSTRACT Sepsis is the clinical syndrome that results from the host response to severe or widespread infection and is a frequent cause of death in veterinary critical care settings. Rapid diagnosis aids early treatment initiation, and hence, how sepsis is defined and identified clinically has implications for patient outcomes.
Robert Goggs   +13 more
wiley   +1 more source

Paraoxonase Genes and Disease

open access: yesAnnals of Medicine, 1999
The paraoxonase gene family contains at least three members, including PON1, PON2 and PON3, which are located on chromosome 7q21.3-22.1. Until recently, there has been little insight into the role of the respective gene products in human physiology and pathology.
openaire   +2 more sources

HDL structure and function is profoundly affected when stored frozen in the absence of cryoprotectants

open access: yesJournal of Lipid Research, 2017
Analysis of structural and functional parameters of HDL has gained significant momentum in recent years because they are stronger predictors of cardiovascular risk than HDL-cholesterol levels. Surprisingly, in most HDL studies, very low attention is paid
Michael Holzer   +4 more
doaj   +1 more source

Surgical impact of laparoscopic and laparotomic elective ovariectomy on inflammatory and oxidative stress biomarkers in anestrus dogs

open access: yesVeterinary Surgery, Volume 55, Issue 5, Page 984-993, July 2026.
Abstract Objective To compare the systemic inflammatory and oxidative stress responses after elective ovariectomy via open surgery (OPEN) or laparoscopy (LAP) in anestrus bitches. Study design Prospective, blinded, randomized clinical trial. Animals A total of 26 healthy bitches.
Alfonso Calabria   +10 more
wiley   +1 more source

Paraoxonase 1 phenotype and paraoxonase activity in asthmatic patients.

open access: yesIranian journal of allergy, asthma, and immunology, 2015
Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics. PON1 activity varies widely among individuals and ethnic groups, partly related to polymorphisms.
GENÇER, NAHİT   +4 more
openaire   +5 more sources

Association Between the Cholesterol–HDL–Glucose (CHG) Index and 90‐Day Functional Outcomes in Patients with Acute Ischemic Stroke

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
The CHG index, derived from total cholesterol, high‐density lipoprotein, and fasting blood glucose, was associated with 90‐day functional outcomes after acute ischemic stroke. ABSTRACT Background: Acute ischemic stroke (AIS) is a major cause of global disability and mortality.
Xinyue Yuan   +5 more
wiley   +1 more source

Antioxidant Status and Serum Prolidase Activity in Women with Subclinical Hypothroidism

open access: yesEndocrinology Research and Practice, 2015
Purpose: Thyroid hormones are associated with the oxidant-antioxidant balance in the organism. Hypothyroidism is associated with impaired collagen turnover. We aimed to evaluate paraoxonase (PON) and arylesterase (ARE) activities, which prevent oxidative
Mehmet Ali Eren   +6 more
doaj   +1 more source

Paraoxonase protection of LDL against peroxidation is independent of its esterase activity towards paraoxon and is unaffected by the Q→R genetic polymorphism

open access: yesJournal of Lipid Research, 1999
High density lipoprotein (HDL)-associated paraoxonase (PON) seems to play a major role in the protection of low density lipoprotein (LDL) against peroxidation by HDL, and the partly purified enzyme exerts a dose-dependent protective effect.
Huibi Cao   +3 more
doaj   +1 more source

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