Results 21 to 30 of about 22,824 (262)
Paraoxonase and Atherosclerosis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2001 Abstract—There is considerable evidence that the antioxidant activity of high density lipoprotein (HDL) is largely due to the paraoxonase-1 (PON1) located on it. Experiments with transgenic PON1 knockout mice indicate the potential for PON1 to protect against atherogenesis.
P N, Durrington +2 more
openaire +2 more sources
Human Paraoxonase-2 (PON2): Protein Functions and Modulation
Antioxidants, 2021 PON1, PON2, and PON3 belong to a family of lactone hydrolyzing enzymes endowed with various substrate specificities. Among PONs, PON2 shows the highest hydrolytic activity toward many acyl-homoserine lactones (acyl-HL) involved in bacterial quorum ...
G. Manco, E. Porzio, T. Carusone
semanticscholar +1 more source
Lipids in Health and Disease, 2021 Recent studies focused on modulating factors of paraoxonase-1 (PON1) activity. In some studies the association between pro-inflammatory markers and PON1 activity was examined, but so far no population-based investigations on this issue have been ...
C. Meisinger +3 more
semanticscholar +1 more source
Effect of Gluten-Free Diet on Serum Antioxidant Levels in Children with Celiac
European Journal of Biology, 2023 Objective: Celiac disease (CD) is an inflammatory condition of the small intestine triggered by the consumption of gluten. A strict gluten-free diet (GFD) is the only treatment that can eliminate CD complications. It was aimed to evaluate the effect of a
Mehmet Ali Gül +5 more
doaj +1 more source
Role of oxidant-antioxidant enzymes in managing the cardiovascular risks in nephrotic syndrome patients [PDF]
Journal of Nephropathology, 2022 Increased reactive oxygen species (ROS) in nephrotic syndrome (NS) are involved in the oxidation of membrane proteins, lipoproteins and several receptor molecules ultimately leading to their functional deficit.
Souparnika Sreelatha +3 more
doaj +1 more source
Slovenian Veterinary Research, 2023 Current findings aimed to find out camel milk's effects on lipid metabolism, expression of the genes for antioxidant enzymes and paraoxonase-1 (PON-1) activity in rats fed diet-containing cholesterol 1%. Therefore, 30 rats were divided into three groups
Sabry M. El-Bahr +2 more
doaj +1 more source
Evaluation of Oxidative Stress Parameters and Antioxidant Status in Coronary Artery Disease Patients [PDF]
Archives of Razi Institute, 2022 A surge in oxidative stress and weakened antioxidant defense contributes to the initiation and progression of Coronary Artery Diseases (CAD). The resultant burst in free radicals causes oxidation of lipoproteins mainly oxidized low-density lipoprotein ...
S Varadhan +3 more
doaj +1 more source
Serum paraoxonase level and paraoxonase polymorphism in patients with acromegaly [PDF]
Redox Report, 2016 Acromegalic patients have increased cardiometabolic risk factors due to an elevation of growth hormone (GH) levels. Human serum paraoxonase (PON), a high-density lipoprotein (HDL)-related enzyme, is one of the major bioscavengers and decreases the oxidation of low-density lipoprotein (LDL), a key regulator in the pathogenesis of atherosclerosis.
Murat Can +8 more
openaire +3 more sources
Paraoxonase/Arylesterase Activity of Serum Paraoxonase-1 and Schizophrenia: A Systematic Review and Meta-Analysis [PDF]
, 2023 The presence of a pro-oxidant state in patients with schizophrenia may account for the increased risk of atherosclerosis and cardiovascular disease in this group and supports the potential utility of circulating biomarkers of oxidative stress for risk ...
Zinellu, Angelo +5 more
core +1 more source
Evidence of Paraoxonases 1, 2, and 3 Expression in Human Ovarian Granulosa Cells
Antioxidants, 2021 Increasing evidence suggests that the antioxidant paraoxonase proteins, PON1, PON2, and PON3, have a role in reproduction and may be synthesized by ovarian cells.
Irantzu Pérez-Ruiz +6 more
doaj +1 more source