Results 11 to 20 of about 22,824 (262)
Caffeine Increases Apolipoprotein A-1 and Paraoxonase-1 but not Paraoxonase-3 Protein Levels in Human-Derived Liver (HepG2) Cells [PDF]
Balkan Medical Journal, 2017 Background: Apolipoprotein A-1, paraoxonase-1 and paraoxonase-3 are antioxidant and anti-atherosclerotic structural high-density lipoprotein proteins that are mainly synthesized by the liver.
Gülben Sayılan Özgün +5 more
doaj +2 more sources
Purification of Human Serum Paraoxonase and Effect of Acetylsalicylic Acid on Paraoxonase Activity [PDF]
Pharmaceutical Biology, 2008 AbstractParaoxonase was purified from human serum using sepharose-4B-l-tyrosine-1-napthylamine affinity chromatography. This enzyme was purified 1797-fold. SDS-polyacrylamide electrophoresis of the enzyme indicates a single protein staining band with an apparent Mr of 43 kDa. The kinetic properties of the purified enzyme were determined.
Demir, Yasar +2 more
openaire +4 more sources
Effect of Glimepiride on Paraoxonase Activity [PDF]
Pharmaceutical Biology, 2006 AbstractIn this study, the effect of glimepiride on serum paraoxonase activity (EC 3.1.8.1.) has been investigated in vitro.. The inhibition and activation effects of this drug on serum paraoxonase activity was measured spectrophotometrically using paraoxon as the substrate.
Nadaroglu, H, Demir, Y, Demir, N
openaire +3 more sources
EXCLI journal, 2011 Human paraoxonase 2 (PON2), which is a member of the paraoxonase family, possesses unique properties that distinguish it from PON1 and PON3. PON2 is ubiquitously expressed in many different tissue types and is highly expressed in the vital organs, such as the heart and lungs.
Permpongpaiboon, Thinnakorn +2 more
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Paraoxonase (PON)-1: a brief overview on genetics, structure, polymorphisms and clinical relevance [PDF]
Vascular Health and Risk Management, 2018 Paraoxonase-1 (PON1) is a high-density lipoprotein-associated esterase and is speculated to play a role in several human diseases including diabetes mellitus and atherosclerosis.
Nelusha Shunmoogam +2 more
semanticscholar +2 more sources
Paraoxonase and arylesterase activities in fibromyalgia [PDF]
Redox Report, 2007 We aimed to evaluate the association of serum paraoxonase and arylesterase activities and oxidative/antioxidative status in patients with fibromyalgia. Forty-two patients with fibromyalgia and 53 healthy controls were included in the study. Serum paraoxonase and arylesterase activities were measured spectrophotometrically.
Altindag, O. +5 more
openaire +5 more sources
Developmental expression of paraoxonase 2 [PDF]
Chemico-Biological Interactions, 2016 Paraoxonase 2 (PON2) is a member of the paraoxonase gene family also comprising PON1 and PON3. PON2 functions as a lactonase and exhibits anti-bacterial as well as antioxidant properties. At the cellular level, PON2 localizes to the mitochondrial and endoplasmic reticulum membranes where it scavenges reactive oxygen species.
Garrick, Jacqueline M. +7 more
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Phytochemicals as Modulators of Paraoxonase-1 in Health and Diseases
Antioxidants, 2022 Chronic diseases such as cardiovascular disease (CVD), atherosclerosis, chronic liver disease, and neurodegenerative diseases are major causes of mortality.
Z. Arab +11 more
semanticscholar +1 more source
Clinical and Experimental Medicine (Testo stampato), 2022 Human serum paraoxonase-1 (PON-1) is a critical antioxidant defense system against lipid oxidation. Decreased PON-1 activity has been associated with systemic oxidative stress in several disease states.
Stefania Bassu +5 more
semanticscholar +1 more source
Study the levels of Leptin, and Adiponectin with Paraoxonase in Obese Individuals (male & female)
Tikrit Journal of Pure Science, 2023 Obesity is a well-known risk factor of metabolic complications and cardiovascular disease. Associations between anthropometric measurements and fat distribution and risk factors for cardiovascular disease have been demonstrated in several populations.
Entedhar R. Sarhat
doaj +1 more source