The Structure and Function of Paraoxonase-1 and Its Comparison to Paraoxonase-2 and -3
Serum paraoxonase-1 (PON1) is the most studied member of the group of paraoxonases (PONs). This enzyme possesses three enzymatic activities: lactonase, arylesterase, and paraoxonase activity.
Ajda Taler-Verčič +2 more
doaj +1 more source
Human Paraoxonase-2 (PON2): Protein Functions and Modulation
PON1, PON2, and PON3 belong to a family of lactone hydrolyzing enzymes endowed with various substrate specificities. Among PONs, PON2 shows the highest hydrolytic activity toward many acyl-homoserine lactones (acyl-HL) involved in bacterial quorum ...
Giuseppe Manco +2 more
doaj +1 more source
Purification and characterisation of a quorum quenching AHL-lactonase from the endophytic bacterium Enterobacter sp. CS66 [PDF]
The quorum quenching (QQ) activity of endophytic bacteria associated with medicinal plants was explored. Extracts of the Gram-negative Enterobacter sp. CS66 possessed potent N-acylhomoserine lactone (AHL) hydrolytic activity in vitro.
Abdelhamid, Yassmin +4 more
core +4 more sources
Signal Disruption Leads to Changes in Bacterial Community Population
The disruption of bacterial signaling (quorum quenching) has been proven to be an innovative approach to influence the behavior of bacteria. In particular, lactonase enzymes that are capable of hydrolyzing the N-acyl homoserine lactone (AHL) molecules ...
Michael Schwab +15 more
doaj +1 more source
β-lactamase enzymes have generated significant interest due to their ability to confer resistance to the most commonly used family of antibiotics in human medicine.
Seydina M. Diene +8 more
doaj +1 more source
Modulation of paraoxonase 1 and 3 expression after moderate exercise training in the rat
Paraoxonases (PONs) are a small family of antioxidant enzymes whose antiatherogenic activity is well known. The aim of the present study was the evaluation of the effects of moderate aerobic training on their expression using a rat model.
Rita Romani +8 more
doaj +1 more source
Kloning Dan Ekspresi Gen Lactonase Dari Pseudomonas Aeruginosa Pa01, Sebagai Kandidat Inhibitor Autoinducer Quorum Sensing [PDF]
Lactonase is an enzyme produced by several bacteria species which targeted and activated acylated homoserine lactones (AHL). AHL-Lactonase will hydrolyze the homoserine Lactone ring from AHL signal which effected to bacterial communicatlon and density ...
Mohamad Fadjar, -
core +1 more source
Field testing of an enzymatic quorum quencher coating additive to reduce biocorrosion of steel
Microbial colonization can be detrimental to the integrity of metal surfaces and lead to microbiologically influenced corrosion. Biocorrosion is a serious problem for aquatic and marine industries in the world and severely affects the maritime ...
Siqian Huang +4 more
doaj +1 more source
Harnessing a versatile robust lactonase for biotechnological applications [PDF]
Extremozymes have gained considerable interest as they could meet industrial requirements. Among these, SsoPox is a hyperthermostable enzyme isolated from the archaeon Sulfolobus solfataricus1. This enzyme is a lactonase catalyzing the hydrolysis of acyl-
Plener, Laure +6 more
core +1 more source
Effects of N-acyl-L-homoserine Lactone Lactonase on Disruption of Preformed Biofilms, Bacterial Recruitment, and Prevention of Biofilms [PDF]
Biofouling is the accumulation of biofilms on inanimate surfaces in aqueous environments. Biofouling can produce economic as well as medicinal consequences such as decreased flow efficiency of chemicals through pipes, increased drag on ships and ...
Boswell, William T.
core +3 more sources

