Results 21 to 30 of about 3,170 (164)
Investigation of Serum Paraoxonase 1 (PON1) Activities in Postprandial Lipemia
Acta Medica Alanya, 2019 Aim: Paraoxonase-1 (PON1) whic is present in HDL structure, is an enzyme that decreases the oxidative stress in atherosclerotic lesions by preventing the HDL and LDL against to ox-idation.
Yahya Altınkaynak +5 more
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AhlX, an N-acylhomoserine Lactonase with Unique Properties [PDF]
Marine Drugs, 2019 N-Acylhomoserine lactonase degrades the lactone ring of N-acylhomoserine lactones (AHLs) and has been widely suggested as a promising candidate for use in bacterial disease control. While a number of AHL lactonases have been characterized, none of them has been developed as a commercially available enzymatic product for in vitro AHL quenching due to ...
Pengfu Liu +8 more
openaire +3 more sources
Lactonase Specificity Is Key to Quorum Quenching in Pseudomonas aeruginosa [PDF]
Frontiers in Microbiology, 2020 The human opportunistic pathogen Pseudomonas aeruginosa orchestrates the expression of many genes in a cell density-dependent manner by using quorum sensing (QS). Two acyl-homoserine lactones (AHLs) are involved in QS circuits and contribute to the regulation of virulence factors production, biofilm formation, and antimicrobial sensitivity.
Benjamin Rémy +7 more
openaire +4 more sources
Quorum Quenching Revisited—From Signal Decays to Signalling Confusion
Sensors, 2012 In a polymicrobial community, while some bacteria are communicating with neighboring cells (quorum sensing), others are interrupting the communication (quorum quenching), thus creating a constant arms race between intercellular communication. In the past
Kok-Gan Chan +4 more
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Frontiers in Cellular and Infection Microbiology, 2023 IntroductionBurkholderia thailandensis is a study model for Burkholderia pseudomallei, a highly virulent pathogen, known to be the causative agent of melioidosis and a potential bioterrorism agent.
Mélanie Gonzales +6 more
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Microbiology Spectrum, 2022 Quorum sensing (QS) is a cell-density-dependent, intercellular communication system mediated by small diffusible signaling molecules. QS regulates a range of bacterial behaviors, including biofilm formation, virulence, drug resistance mechanisms, and ...
Rakesh Sikdar, Mikael H. Elias
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Effects of Signal Disruption Depends on the Substrate Preference of the Lactonase
Frontiers in Microbiology, 2020 Many bacteria produce and use extracellular signaling molecules such as acyl homoserine lactones (AHLs) to communicate and coordinate behavior in a cell-density dependent manner, via a communication system called quorum sensing (QS).
Kathleen Mahan +6 more
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Study of Oxidative Stress Marker Serum Paraoxonase in Metabolic Syndrome
Endocrinology Research and Practice, 2016 Purpose: The metabolic syndrome (MetS) is a constellation of interrelated risk factors of metabolic origin that appear to promote development of cardiovascular disease.
Mohit Rojekar +2 more
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Differential active site loop conformations mediate promiscuous activities in the lactonase SsoPox.
PLoS ONE, 2013 Enzymes are proficient catalysts that enable fast rates of Michaelis-complex formation, the chemical step and products release. These different steps may require different conformational states of the active site that have distinct binding properties ...
Julien Hiblot +3 more
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Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus
Frontiers in Microbiology, 2018 In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. This mutant couldn’t grow in the absence of MVA.
Sebastian Reichert +11 more
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