Results 31 to 40 of about 3,170 (164)

Lyso-DGTS Lipid Derivatives Enhance PON1 Activities and Prevent Oxidation of LDL: A Structure–Activity Relationship Study

open access: yesAntioxidants, 2022
Paraoxonase 1 (PON1) plays a role in regulating reverse cholesterol transport and has antioxidative, anti-inflammatory, antiapoptotic, vasodilative, and antithrombotic activities.
Ali Khattib   +4 more
doaj   +1 more source

Modification and Assembly of a Versatile Lactonase for Bacterial Quorum Quenching [PDF]

open access: yesMolecules, 2018
This work sets out to provide a self-assembled biopolymer capsule activated with a multi-functional enzyme for localized delivery. This enzyme, SsoPox, which is a lactonase and phosphotriesterase, provides a means of interrupting bacterial communication pathways that have been shown to mediate pathogenicity.
Rhoads, Melissa K.   +6 more
openaire   +4 more sources

Enzymatic quorum quenching increases antibiotic susceptibility of multidrug resistant Pseudomonas aeruginosa

open access: yesIranian Journal of Microbiology, 2011
Background and Objectives: There is increasing emergence of multidrug resistant Pseudomonas aeruginosa (MDRPA) strains and drug resistance is positively-correlated with biofilm-forming ability. Since about 10% of P.
P Sharma, S Kiran, K Harjai, N Capalash
doaj  

Multiple Quorum Quenching Enzymes Are Active in the Nosocomial Pathogen Acinetobacter baumannii ATCC17978

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Acinetobacter baumannii presents a typical luxI/luxR quorum sensing (QS) system (abaI/abaR) but the acyl-homoserine lactone (AHL) signal profile and factors controlling the production of QS signals in this species have not been determined yet.
Celia Mayer   +5 more
doaj   +1 more source

Distribution of Paraoxonase 1 polymorphisms and activities in obese patients

open access: yesRomanian Journal of Laboratory Medicine, 2013
Obiectivul studiului a fost de investigarea fenotipului şi genotipului PON1 la pacienţii români cu obezitate abdominală. Material şi metodă. Loturile din studiu au constat din 88 de pacienţi cu obezitate abdominală şi 46 subiecţi cu circumferinţă ...
Ciumărnean Lorena   +6 more
doaj   +1 more source

Bacterial Quorum-Quenching Lactonase Hydrolyzes Fungal Mycotoxin and Reduces Pathogenicity of Penicillium expansum—Suggesting a Mechanism of Bacterial Antagonism

open access: yesJournal of Fungi, 2021
Penicillium expansum is a necrotrophic wound fungal pathogen that secrets virulence factors to kill host cells including cell wall degrading enzymes (CWDEs), proteases, and mycotoxins such as patulin. During the interaction between P.
Shlomit Dor   +2 more
doaj   +1 more source

Biofunctionalization of Silver Nanoparticles With Lactonase Leads to Altered Antimicrobial and Cytotoxic Properties

open access: yesFrontiers in Molecular Biosciences, 2019
Background: N-acylated homoserine lactone lactonase which cleave the Acyl homoserine lactone molecules produced by biofilm-forming pathogens and silver nano-particles (AgNPs), are known for their antibacterial effect against several Gram-positive and ...
Kshitiz Gupta, Sanjay Chhibber
doaj   +1 more source

Enzymes with Lactonase Activity against Fungal Quorum Molecules as Effective Antifungals

open access: yesBiomolecules
Since the growing number of fungi resistant to the fungicides used is becoming a serious threat to human health, animals, and crops, there is a need to find other effective approaches in the eco-friendly suppression of fungal growth.
Elena Efremenko   +4 more
doaj   +1 more source

Substrate Specificity of Actinoplanes Antibiotic Peptide Lactonases [PDF]

open access: yesApplied Microbiology, 1969
A constitutive peptide lactonase from Actinoplanes missouriensis hydrolyzed echinomycin, stendomycin, thiostrepton, vernamycin B, staphylomycin S, and etamycin. An induced lactonase hydrolyzed actinomycin but not the other peptide lactones.
D, Perlman, C T, Hou
openaire   +2 more sources

Quorum Quenching Lactonase Strengthens Bacteriophage and Antibiotic Arsenal Against Pseudomonas aeruginosa Clinical Isolates

open access: yesFrontiers in Microbiology, 2019
Many bacteria use quorum sensing (QS), a bacterial communication system based on the diffusion and perception of small signaling molecules, to synchronize their behavior in a cell-density dependent manner.
Sonia Mion   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy