Results 41 to 50 of about 6,201 (226)

Evidence for Complex Interplay between Quorum Sensing and Antibiotic Resistance in Pseudomonas aeruginosa

Microbiology Spectrum, 2022
Quorum sensing (QS) is a cell-density-dependent, intercellular communication system mediated by small diffusible signaling molecules. QS regulates a range of bacterial behaviors, including biofilm formation, virulence, drug resistance mechanisms, and ...
Rakesh Sikdar, Mikael H. Elias
doaj   +1 more source

Effects of Signal Disruption Depends on the Substrate Preference of the Lactonase

Frontiers in Microbiology, 2020
Many bacteria produce and use extracellular signaling molecules such as acyl homoserine lactones (AHLs) to communicate and coordinate behavior in a cell-density dependent manner, via a communication system called quorum sensing (QS).
Kathleen Mahan, Ryan Martinmaki, Isabel Larus, Rakesh Sikdar, Jordan Dunitz, Jordan Dunitz, Mikael Elias   +6 more
doaj   +1 more source

Controlled vocabularies in bioinformatics: A case study in the Gene Ontology [PDF]

, 2004
The automatic integration of information resources in the life sciences is one of the most challenging goals facing biomedical informatics today. Controlled vocabularies have played an important role in realizing this goal, by making it possible to draw ...
Anand Kumar, Bada, Barry Smith, Gene Ontology Consortium, Grenon, Hahn, Kumar, Ogren, Schulz, Smith, Smith, Smith   +11 more
core   +1 more source

Study of Oxidative Stress Marker Serum Paraoxonase in Metabolic Syndrome

Endocrinology Research and Practice, 2016
Purpose: The metabolic syndrome (MetS) is a constellation of interrelated risk factors of metabolic origin that appear to promote development of cardiovascular disease.
Mohit Rojekar, Mukund Mogarekar, Arati Adhe-Rojekar   +2 more
doaj   +1 more source

AidP, a novel N-Acyl Homoserine Lactonase gene from Antarctic Planococcus sp. [PDF]

, 2017
Planococcus is a Gram-positive halotolerant bacterial genus in the phylum Firmicutes, commonly found in various habitats in Antarctica. Quorum quenching (QQ) is the disruption of bacterial cell-to-cell communication (known as quorum sensing), which has ...
Chan, Kok-Gan, Convey, Peter, Ee, Robson, Lim, Yan-Lue, Pearce, David, See-Too, Wah Seng, Yin, Wai-Fong   +6 more
core   +2 more sources

Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Bioelectronic systems that enable seamless communication between electronic devices and living systems represent a transformative frontier in biotechnology. Among available methodologies, redox based signaling offers unique advantages due to its ubiquity in biology and compatibility with standard electrochemical equipment, expanding on ...
Eric VanArsdale, Monica Chu, Sally Wang, Divya Muthusamy, Eric Wold, Yi Liu, G. F. Payne, Tanya Tschirhart, W. E. Bentley   +8 more
wiley   +1 more source

Differential active site loop conformations mediate promiscuous activities in the lactonase SsoPox.

PLoS ONE, 2013
Enzymes are proficient catalysts that enable fast rates of Michaelis-complex formation, the chemical step and products release. These different steps may require different conformational states of the active site that have distinct binding properties ...
Julien Hiblot, Guillaume Gotthard, Mikael Elias, Eric Chabriere   +3 more
doaj   +1 more source

Quorum-sensing regulates biofilm formation in Vibrio scophthalmi [PDF]

, 2013
Background: In a previous study, we demonstrated that Vibrio scophthalmi, the most abundant Vibrio species among the marine aerobic or facultatively anaerobic bacteria inhabiting the intestinal tract of healthy cultured turbot (Scophthalmus maximus ...
Blanch i Gisbert, Anicet, García Aljaro, Cristina, Melado Rovira, Silvia, Milton, Debra L.   +3 more
core   +1 more source

Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers, Isabel O. de Moya Clark, Tomás Cavaco, Vivian Nemanič, Beatrice Tagliabue, Ainhoa Valero‐Abad, Wiebe M. Wennekers, Mengqiu Zhang, Koen Van Zwet, Sanne Abeln, Sofia Moco, Caroline E. Paul, Halima Mouhib, Richard A. Notebaart, Eddy J. Smid, Bas Teusink, Herwig Bachmann   +16 more
wiley   +1 more source

Inhibiting N-acyl-homoserine lactone synthesis and quenching Pseudomonas quinolone quorum sensing to attenuate virulence [PDF]

, 2015
YesBacteria sense their own population size, tune the expression of responding genes, and behave accordingly to environmental stimuli by secreting signaling molecules. This phenomenon is termed as quorum sensing (QS).
Antunes, Atkinson, Atkinson, Bera, Brackman, Brackman, Calfee, Cao, Chang, Chhabra, Chu, Chun, Chung, Cugini, Cugini, Cámara, Decho, Deng, Diggle, Diggle, Dong, Dong, Dong, Drees, Dulcey, Dworkin, Déziel, Fuqua, Fuqua, García-Contreras, González, Gould, Hanzelka, Heeb, Hoang, Holm, Joint, Kalia, Kalia, Kendall, Koh, Kumar, LaSarre, Lee, Lesic, Maddocks, McKnight, Miller, Moreira, Nazzaro, Ng, Okkotsu, Ortori, Ozer, Parsek, Pesci, Pustelny, Rampioni, Rasmussen, Schweizer, Singh, Singh, Singh, Soh, Sperandio, Srivastava, Starkey, Tiaden, Twigg, Urbanczyk, Vakulskas, Vandeputte, Wang, Watson, Williams, Winstanley, Xiao, Yang, Zhang, Zheng   +79 more
core   +5 more sources