Results 11 to 20 of about 3,170 (164)

The Structure and Function of Paraoxonase-1 and Its Comparison to Paraoxonase-2 and -3

open access: yesMolecules, 2020
Serum paraoxonase-1 (PON1) is the most studied member of the group of paraoxonases (PONs). This enzyme possesses three enzymatic activities: lactonase, arylesterase, and paraoxonase activity.
Ajda Taler-Verčič   +2 more
doaj   +1 more source

Human Paraoxonase-2 (PON2): Protein Functions and Modulation

open access: yesAntioxidants, 2021
PON1, PON2, and PON3 belong to a family of lactone hydrolyzing enzymes endowed with various substrate specificities. Among PONs, PON2 shows the highest hydrolytic activity toward many acyl-homoserine lactones (acyl-HL) involved in bacterial quorum ...
Giuseppe Manco   +2 more
doaj   +1 more source

Specificity and Enzyme Kinetics of the Quorum-quenching N-Acyl Homoserine Lactone Lactonase (AHL-lactonase) [PDF]

open access: yesJournal of Biological Chemistry, 2004
N-Acyl homoserine lactone (AHL) quorum-sensing signals are the vital elements of bacterial quorum-sensing systems, which regulate diverse biological functions, including virulence. The AHL-lactonase, a quorumquenching enzyme encoded by aiiA from Bacillus sp., inactivates AHLs by hydrolyzing the lactone bond to produce corresponding N-acyl homoserines ...
Wang, L.-H.   +3 more
openaire   +2 more sources

Signal Disruption Leads to Changes in Bacterial Community Population

open access: yesFrontiers in Microbiology, 2019
The disruption of bacterial signaling (quorum quenching) has been proven to be an innovative approach to influence the behavior of bacteria. In particular, lactonase enzymes that are capable of hydrolyzing the N-acyl homoserine lactone (AHL) molecules ...
Michael Schwab   +15 more
doaj   +1 more source

Origin, Diversity, and Multiple Roles of Enzymes with Metallo-β-Lactamase Fold from Different Organisms

open access: yesCells, 2023
β-lactamase enzymes have generated significant interest due to their ability to confer resistance to the most commonly used family of antibiotics in human medicine.
Seydina M. Diene   +8 more
doaj   +1 more source

Field testing of an enzymatic quorum quencher coating additive to reduce biocorrosion of steel

open access: yesMicrobiology Spectrum, 2023
Microbial colonization can be detrimental to the integrity of metal surfaces and lead to microbiologically influenced corrosion. Biocorrosion is a serious problem for aquatic and marine industries in the world and severely affects the maritime ...
Siqian Huang   +4 more
doaj   +1 more source

Modulation of paraoxonase 1 and 3 expression after moderate exercise training in the rat

open access: yesJournal of Lipid Research, 2009
Paraoxonases (PONs) are a small family of antioxidant enzymes whose antiatherogenic activity is well known. The aim of the present study was the evaluation of the effects of moderate aerobic training on their expression using a rat model.
Rita Romani   +8 more
doaj   +1 more source

Low Serum Paraoxonase-1 Lactonase and Arylesterase Activities in Obese Children and Adolescents

open access: yesRomanian Journal of Laboratory Medicine, 2015
Serum paraoxonase-1 (PON1) binds mainly to high density lipoproteins (HDLs) and protects low density lipoproteins (LDLs) against oxidation. While paraoxonase and arylesterase activities are traditionally assayed, lactonase activity, accounting for ...
Sandor Raluca   +6 more
doaj   +1 more source

High yield expression of an AHL-lactonase from Bacillus sp. B546 in Pichia pastoris and its application to reduce Aeromonas hydrophila mortality in aquaculture

open access: yesMicrobial Cell Factories, 2010
Background Aeromonas hydrophila is a serious pathogen and can cause hemorrhagic septicemia in fish. To control this disease, antibiotics and chemicals are widely used which can consequently result in "superbugs" and chemical accumulation in the food ...
Bai Yingguo   +4 more
doaj   +1 more source

Rhodococcus erythropolis and Its γ-Lactone Catabolic Pathway: An Unusual Biocontrol System That Disrupts Pathogen Quorum Sensing Communication

open access: yesAgronomy, 2013
Rhodococcus erythropolis is an environmental Gram-positive Actinobacterium with a versatile metabolism involved in various bioconversions and degradations.
Xavier Latour   +4 more
doaj   +1 more source

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