Challenges faced by health policymakers responding to COVID-19 in remote communities in Northwest Territories, Canada. [PDF]
Zakkar M +8 more
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Insights Into Veterans' Motivations and Hesitancies for COVID-19 Vaccine Uptake: A Mixed-Methods Analysis. [PDF]
Barrett AK +13 more
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An educated mind is a requirement for good general practice. [PDF]
Papanikitas A.
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
How Do Clinicians Use Quotations in Goals of Care Notes? [PDF]
Piscitello GM +3 more
europepmc +1 more source
Resilient nursing in ICU: Aadaptive practices beyond IPC protocols for MDRO management. A qualitative study. [PDF]
Cappelli E +3 more
europepmc +1 more source
Health responsibility among marginalized women in Mashhad, northeastern Iran: a critical ethnographic study. [PDF]
Rastgoo F +3 more
europepmc +1 more source
Perspectives of Women with Breast Cancer and Healthcare Providers Participating in an Adherence-Enhancing Program for Adjuvant Endocrine Therapy: A Qualitative Study. [PDF]
Turcotte V +8 more
europepmc +1 more source

