Digital finance, financial regulation and transformation of R&D achievements. [PDF]
HeliyonXie Z, Wu Y.
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Taiwan's Smart Healthcare Value Chain: AI Innovation from R&D to Industry Deployment. [PDF]
Healthcare (Basel)Lin TM, Yang HW, Han CC, Lin CS.
europepmc +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
R&D Cooperation Cycles and Interaction Friendly R&D Structure
R&D Cooperation Cycles and Interaction Friendly R&D Structureidentifier:oai:t2r2.star.titech.ac.jp ...
openaire +1 more source
A global dataset of public agricultural R&D investment: 1960-2022. [PDF]
Sci Datavan Dijk M, Fuglie K, Heisey PW, Deng H.
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Trends in National R&D Projects on Biomimetics in South Korea. [PDF]
Biomimetics (Basel)Na H, Kim E.
europepmc +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
The impact of the centralized volume-based procurement policy on Chinese pharmaceutical manufacturing firms' R&D investment: A difference-in-differences approach. [PDF]
PLoS OneQiu F, Chen S, Li Y, Wang X, Zhu M.
europepmc +1 more source