Results 141 to 150 of about 8,764,171 (325)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Blood and urine multi-omics analysis of the impact of e-vaping, smoking, and cessation: from exposome to molecular responses

Scientific Reports
Cigarette smoking is a major preventable cause of morbidity and mortality. While quitting smoking is the best option, switching from cigarettes to non-combustible alternatives (NCAs) such as e-vapor products is a viable harm reduction approach for ...
Carine Poussin, Bjoern Titz, Yang Xiang, Laurel Baglia, Rachel Berg, David Bornand, Mohammed-Amin Choukrallah, Timothy Curran, Sophie Dijon, Eric Dossin, Remi Dulize, Doris Etter, Maria Fatarova, Loyse Felber Medlin, Adrian Haiduc, Edina Kishazi, Aditya R. Kolli, Athanasios Kondylis, Emmanuel Kottelat, Csaba Laszlo, Oksana Lavrynenko, Yvan Eb-Levadoux, Catherine Nury, Dariusz Peric, Melissa Rizza, Thomas Schneider, Emmanuel Guedj, Florian Calvino, Nicolas Sierro, Philippe Guy, Nikolai V. Ivanov, Patrick Picavet, Sherry Spinelli, Julia Hoeng, Manuel C. Peitsch   +34 more
doaj   +1 more source

Study on the Product Symbol System for Brand R&D

, 2009
Qin Wang
openalex   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Mammals — Their Latin Names Explained: A guide to animal classification by A. F. Gotch; Blandford, £5.95. - Key Works to the Fauna and Flora of the British Isles and Northwestern Europe, edited by G. J. Kerrich, D. L. Hawksworth and R. W. Sims. Systematics Association Special Volume no 9. Academic Press, £7.80. [PDF]

, 1979
Richard Fitter
openalex   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Industrial R&D in Italy: Exploration and Exploitation Strategies in Industrial R&D [PDF]

This paper discusses four types of strategic decisions in technology management in established firms. It is well known that deciding between exploration and exploitation in R&D, and eventually combining the two strategies, is a crucial issue. However, we
Alberto Di Minin, Andrea Piccaluga, Fabrizio Cesaroni   +2 more
core  

Aa mandonii: Trujillo, D. & Meneses, R.

, 2018
IUCN
openalex   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

State aid to investment and R&D [PDF]

The prohibition of state aid to investment and R&D in an integrated market such as the European Community is analysed in a Cournot oligopoly model where firms undertake investment or R&D to reduce their costs.
David R Collie
core