Results 121 to 130 of about 8,764,171 (325)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Riesz transforms, Cauchy-Riemann systems and amalgam Hardy spaces

open access: yes, 2018
In this paper we study Hardy spaces $\mathcal{H}^{p,q}(\mathbb{R}^d ...
Assaubay, Al-Tarazi   +3 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Synergistic Innovative Therapies in Dermatology: Integrating Platelet Derivatives, Biomaterials, and Exogenous Bioactive Substances for Enhancing Skin Repair and Regeneration

open access: yesDrug Design, Development and Therapy
Eduardo Anitua,1,2 Roberto Tierno,1,2 Gorka Orive,1,2 Mohammad Hamdan Alkhraisat1,2 1Department of Regenerative Medicine, BTI Biotechnology Institute, Vitoria, Alava, Spain; 2Department of Regenerative Medicine, University Institute for Regenerative ...
Anitua E   +3 more
doaj  

Quasi-statically actuated MEMS scanner with concentric vertical comb electrodes

open access: yesMicro and Nano Systems Letters
A quasi-static (QS) MEMS mirror scanner with concentric vertical combs (CVC) is presented. The increase rate of overlapped area of the CVC, tends to show larger values and more uniform than that of conventional vertical combs, resulting in improved ...
Daehwan Chae   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

On the robustness of R&D [PDF]

open access: yes, 2012
Alternative models of productivity predict a range of its determinants besides that of research and development (R&D). We investigate the robustness of R&D vis-à-vis a dozen productivity determinants in a panel of 16 Organisation for Economic Co-operation and Development (OECD) countries through panel cointegration, bootstrap simulations and extensive ...
Luintel, Kul   +3 more
openaire  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Corporate R&D and Firm Efficiency: Evidence from Europe’s Top R&D Investors [PDF]

open access: yes
The main objective of this study is to investigate the impact of corporate R&D activities on firms' performance, measured by labour productivity. To this end, the stochastic frontier technique is applied, basing the analysis on a unique unbalanced ...
Kumbhakar, Subal C.   +4 more
core  

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