Results 91 to 100 of about 355,047 (195)

EpCAM+ Extracellular Vesicle PD‐L1 Dynamics as a Predictive Biomarker of Immune Checkpoint Blockade Response

open access: yesAdvanced Science, EarlyView.
A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun   +15 more
wiley   +1 more source

Non‐Line‐of‐Sight Passive Ammonia Sensor Loaded With MXene/In2O3 Composites for Agricultural Products Quality Deterioration Detection

open access: yesAdvanced Science, EarlyView.
This study presents a flexible, battery‐free passive RFID sensing platform for NLoS monitoring of quality deterioration in fresh agricultural products. It utilizes a structurally decoupled spiral antenna‐LC electrode architecture to suppress electromagnetic interference caused by packaging.
Guoping Hu   +4 more
wiley   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

open access: yesAdvanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu   +10 more
wiley   +1 more source

Interface Charge Induced Multifunctional Manipulations in Metals

open access: yesAdvanced Science, EarlyView.
Voltage‑controlled interface charge enables giant, reversible modulation of magnetic anisotropy, magnetization, and resistivity in common metals. Space‑separated ions and electrons accumulate at interfaces, producing strong interfacial capacitor effect and high‑density electrons injection.
Qiang Cao   +10 more
wiley   +1 more source

Volatile ZrO2 Antiferroelectric Tunnel Junctions for Rapid, Energy‐Efficient Physical Reservoir Computing

open access: yesAdvanced Science, EarlyView.
An antiferroelectric tunnel junction serves as a reservoir computing node, where field‐induced phase transitions and spontaneous ZrO2 relaxation deliver nonlinear fading memory. An In‐Ga‐Zn oxide interlayer enlarges the memory margin and multibit state richness.
Taegyu Kwon   +13 more
wiley   +1 more source

Pautas publicitarias

open access: yesEscena. Revista de las artes, 2017
Radio Universidad. Revista Herencia UCR
doaj   +1 more source

Pattern‐Aware Intelligence Enables Nondestructive, Rapid Quantification of High‐Aspect‐Ratio Silicon Etching

open access: yesAdvanced Science, EarlyView.
Pattern‐dependent etching is converted into a physical prior for intelligent reconstruction of high‐aspect‐ratio silicon structures. Combining YOLO‐Pose feature extraction with a topography network, the framework retrieves depth, sidewall angle, and scallop texture from minimal destructive observations, enabling accurate cross‐scale metrology and near ...
Shuyan He   +4 more
wiley   +1 more source

Red Blood Cells as Endogenous Biotweezers for Optical Micromanipulation In Vivo

open access: yesAdvanced Science, EarlyView.
By synergistically integrating the long‐distance manipulation fiber probe (LDMFP) and endogenous red blood cells (RBCs) as biocompatible optical elements, a natural RBC biotweezer was developed for the desired microparticle manipulation and immune cell activation within living vasculature, which might offer an alternative tool for intravital optical ...
Tong Yang   +9 more
wiley   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

open access: yesAdvanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo   +10 more
wiley   +1 more source

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