Results 111 to 120 of about 364,602 (244)

Strategi Jaringan Radio Komunitas Indonesia (JRKI) dalam Menyelamatkan Eksistensi Radio Komunitas

open access: yesKomunikator, 2015
Community radio movement could be considered as media of resistance / counter hegemony. However, in fact, some community radios are far from expectations.
ARYO SUBARKAH EDDYONO
doaj  

El model de negoci en cadena a Catalunya : de l'èxit radiofònic al fracàs televisiu [PDF]

open access: yes, 2012
Al llarg dels anys dos mil, quatre empreses de televisió local han intentat aplicar a Catalunya el model de negoci en cadena. Sorgit a la indústria radiofònica als anys vint del segle passat, es basa en l'agregació d'emissores per poder emetre en cadena ...
Bonet Bagant, Montse   +1 more
core   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

open access: yesAdvanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang   +10 more
wiley   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

open access: yesAdvanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance   +17 more
wiley   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang   +12 more
wiley   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

open access: yesAdvanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann   +15 more
wiley   +1 more source

Salut i ràdio : anàlisi de la pràctica periodística [PDF]

open access: yes, 2006
Les ràdios generalistes, públiques i privades, emeten productes de caràcter informatiu i de divulgació que aborden el tema de salut. L'article mostra, de manera resumida, els resultats d'una recerca sobre el tractament i difusió radiofònic d'aquests ...
Gutiérrez García, María.   +1 more
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Mid-infrared Properties of Narrow-line Seyfert 1 Galaxies Detected by LoTSS DR2

open access: yesThe Astrophysical Journal
Narrow-line Seyfert 1 galaxies (NLS1s), a subclass of active galactic nuclei (AGNs) in an early stage of the accretion process, are also found to host relativistic jets. However, currently known jetted NLS1s are rare. The majority of NLS1s are undetected
Xu-Liang Fan
doaj   +1 more source

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