Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The experience of a multidisciplinary team in welcoming vulnerable migrants in a rural Italian reception centre: a study using multidimensional textual analysis. [PDF]
BMC NursFigura M +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Quality indicators and turnaround time for blood culture in pediatric patients: 1 year of monitoring in 19 Chinese hospitals. [PDF]
BMC PediatrWu H +8 more
europepmc +1 more source
Evolution of the general practice receptionist role and online services: a qualitative study. [PDF]
Br J Gen PractStockwell S +8 more
europepmc +1 more source
A Resilient Distributed Pareto-Based PSO for Edge-UAVs Deployment Optimization in Internet of Flying Things. [PDF]
Sensors (Basel)Zerrougui S, Zaidi S, Calafate CT.
europepmc +1 more source
Optimization Method for Secrecy Capacity of UAV Relaying Based on Dynamic Adjustment of Power Allocation Factor. [PDF]
Sensors (Basel)Hao Y +6 more
europepmc +1 more source
Ambient Electromagnetic Wave Energy Harvesting Using Human Body Antenna for Wearable Sensors. [PDF]
Sensors (Basel)Muramatsu D, Amano K.
europepmc +1 more source