Results 221 to 230 of about 230,644 (244)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
High-Resolution Spatiotemporal-Coded Differential Eddy-Current Array Probe for Defect Detection in Metal Substrates. [PDF]
Sensors (Basel)Ouyang Q, Meng Y, Huang L, Li Y.
europepmc +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Study and Optimal Design of the Integrated 37° Unidirectional SV-EMAT for Rapid Rail Flaw Detection. [PDF]
Sensors (Basel)Yuan W.
europepmc +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Evaluation of special educational needs and disability provision in English primary schools using administrative health and education data in the ECHILD database. [PDF]
Int J Popul Data SciGilbert R +19 more
europepmc +1 more source
The impact of latent tuberculosis screening programmes for migrant populations in high income, low burden countries. [PDF]
PLoS OneTaylor AE +3 more
europepmc +1 more source