Results 81 to 90 of about 230,644 (244)

«Morgant le geant»: mise en livre et réception programmée de Pulci en France

open access: yesCarte Romanze, 2014
Morgante Maggiore a été traduit pour la première fois en français en 1519. On compte dix rééditions durant le XVIe siècle de cette traduction anonyme sinon effectuée dans un milieu parisien, du moins publiée à Paris.
Pascale Mounier
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Les… interrogations de Philippe Djian [PDF]

open access: yesSynergies Algerie, 2017
Depuis 2012, les récits fictifs ou métatextuels de l’écrivain français Philippe Djian témoignent d’une volonté d’abolir l’usage orthodoxe de la ponctuation. L’auteur pense que les signes épilinguistiques ont une force sémantique aussi importante que les
Myriam Bouchoucha
doaj  

L'EXPÉRIENCE DU NET ART CADRES D'UNE RECEPTION NEGOCIÉE Une sociologie de l'usage des TIC

open access: yes, 2006
Cet article propose de qualifier les rites et rythmes inhérents à la « mise en œuvre » de l'art avec Internet. L'objectif est de saisir la variété des opérations mobilisées pour la configuration et circulation de ces œuvres entre l'artiste et des ...
Fourmentraux, Jean-Paul
core   +1 more source

Repérages sur la réception et ses multiples paradigmes [PDF]

open access: yes, 2009
Au cœur de toute communication, réside le mystère de sa réception : qui consomme quoi et comment ? Qui influence qui ? Pour quels effets ? La question n'est pas propre aux médias ; elle vient de la littérature, du spectacle vivant, bref de toute activité
Méadel, Cécile
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Women Artists and the 1944 Canadian Army Art Exhibition [PDF]

open access: yes, 2012
In 1944, the Canadian Army held an art exhibition in Ottawa. Among the 33 exhibitors were five women: Cathryne Blackley, Beulah Jaenicke, Molly Lamb, H.E. Herbert, and Mary Wilson.
Brandon, Laura
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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