Results 81 to 90 of about 542,938 (244)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Etude électrophysiologique préliminaire de la régénération du nerf alvéolaire inférieur [PDF]

open access: yes, 2010
Un protocole expérimental a été mené sur 8 lapins afin d’évaluer la régénération du nerf alvéolaire inférieur (IAN) 6 mois après section complète et suture conventionnelle.
Jean-Claude Libersa   +3 more
core   +1 more source

Potentialités de régénération naturelle des feuillus sous épicéas ou douglas [PDF]

open access: yes, 2006
[Departement_IRSTEA]GT [TR1_IRSTEA]SET / BIOFORNational audienceUne étude menée en Auvergne sous le couvert d'épicéas et de douglas montre que la régénération naturelle de feuillus, et notamment du hêtre, est possible sous couvert de résineux. La lumière,
Landré, Fabrice, Balandier, Philippe
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Effect of irrigation on the recovery of young argan plants after transplanting to the field

open access: yesRevue Marocaine des Sciences Agronomiques et Vétérinaires, 2018
This work is part of the research program supporting the '' Arganier Project ''. It is coordinated by the Agrotechnologies Association of Souss Massa Draa (Agrotech) in partnership with a consortium of researchers on the argan tree.
Ahmed WIFAYA   +2 more
doaj  

Immunoneutralization of TGFβ1 Improves Skeletal Muscle Regeneration: Effects on Myoblast Differentiation and Glycosaminoglycan Content

open access: yesInternational Journal of Cell Biology, 2009
When injured by crushing, the repair of the slow-twitch soleus rat muscle, unlike the fast-twitch EDL, is associated with fibrosis. As TGFβ1, whose activity can be controlled by glycosaminoglycans (GAG), plays a major role in fibrosis, we hypothesized ...
M. Zimowska   +5 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Régénération naturelle acquise en forêt dense sempervirente [PDF]

open access: yes, 1993
Dans le présent exposé, la répartition et la densité de la régénération naturelle acquise en forêt sempervirente de Côte d'Ivoire seront ...
Diahuissié, Aimé   +2 more
core  

Régénération des huiles lubrifiantes usagées par processus de traitement à l’acide

open access: yesRevue des Énergies Renouvelables, 2014
Les huiles sont obtenues par distillation des produits lourds du pétrole. Avec la baisse de la production de réserves mondiales de pétrole, la nécessité se pose plus que jamais, de recycler des huiles lubrifiantes usagées.
R. Mazouzi   +3 more
doaj  

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