Results 141 to 150 of about 18,552 (216)

Next‐Generation Manufacturing: The Evolving Role of Biocatalysis in AstraZeneca

open access: yesChemBioChem, Volume 27, Issue 17, 14 September 2026.
Biocatalysis is strengthening AstraZeneca's manufacture of active pharmaceutical ingredients through faster development, robust scale‐up, and lower environmental impact. Case studies illustrate where biocatalysis delivers greatest value, while enabling platforms, teams, and partnerships shape its next phase.
Alba Diaz‐Rodriguez   +4 more
wiley   +1 more source

Silylium‐Ion‐Initiated Disulfidation of Internal Alkynes With Disulfides

open access: yesChemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Silylium‐ion initiation enables the disulfidation of internal alkynes with diaryl disulfides. The catalytic turnover is maintained by the sulfonium ion ArS(ArSSAr)+ as a sulfenium‐ion carrier that reacts with an alkyne to form a thiirenium ion. Its ring opening by disulfide addition yields the 1,2‐bis(arylthio)‐substituted alkene product with E:Z > 95 ...
Dáiríne M. Morgan   +2 more
wiley   +1 more source

Dual-Hybrid Treatment Approach for Peri-Implant Hard and Soft Tissue Stability. [PDF]

open access: yesJ Esthet Restor Dent
Gallucci GO   +5 more
europepmc   +1 more source

The Cyano‐Diels–Alder Reaction: From Nitrile Activation to Functional Molecular Architectures

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 34, 11 September 2026.
This Concept Article presents the evolution of the cyano‐Diels–Alder reaction from its early examples to its current development as a valuable synthetic tool for the preparation of N‐heterocycles, fused polycycles and functional chromophores, tracing the key breakthroughs that have transformed this underexplored transformation into a relevant platform ...
Giovanni Bottari
wiley   +1 more source

Strain-Release Pentafluorosulfanylation of Carbonyl-Containing Disubstituted Bicyclobutanes: A Fortuitous Path to SF<sub>5</sub>-Containing Oxa[2.1.1]bicyclohexanes. [PDF]

open access: yesAngew Chem Int Ed Engl
A regio‐ and diastereoselective method for strain‐release pentafluorosulfanylation of carbonyl‐containing 1,3‐disubstituted [1.1.0]bicyclobutanes (BCBs) was developed that led to several fortuitous discoveries. For instance, the resultant SF5‐cyclobutanes (SF5‐CBs) exhibit close SF5⋯C═X contacts (X = C, N, O) and provide synthetic access to a new class
Stephens AM   +9 more
europepmc   +2 more sources

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