Stereocontrolled entry to borylated piperidines <i>via</i> stepwise dearomative carboboration of pyridines. [PDF]
Khalse LD +4 more
europepmc +1 more source
Next‐Generation Manufacturing: The Evolving Role of Biocatalysis in AstraZeneca
Biocatalysis is strengthening AstraZeneca's manufacture of active pharmaceutical ingredients through faster development, robust scale‐up, and lower environmental impact. Case studies illustrate where biocatalysis delivers greatest value, while enabling platforms, teams, and partnerships shape its next phase.
Alba Diaz‐Rodriguez +4 more
wiley +1 more source
Pd-catalyzed regio- and enantioselective allylation of cyclic allylboronates. [PDF]
Zhang C +4 more
europepmc +1 more source
Silylium‐Ion‐Initiated Disulfidation of Internal Alkynes With Disulfides
Silylium‐ion initiation enables the disulfidation of internal alkynes with diaryl disulfides. The catalytic turnover is maintained by the sulfonium ion ArS(ArSSAr)+ as a sulfenium‐ion carrier that reacts with an alkyne to form a thiirenium ion. Its ring opening by disulfide addition yields the 1,2‐bis(arylthio)‐substituted alkene product with E:Z > 95 ...
Dáiríne M. Morgan +2 more
wiley +1 more source
Dual-Hybrid Treatment Approach for Peri-Implant Hard and Soft Tissue Stability. [PDF]
Gallucci GO +5 more
europepmc +1 more source
The Cyano‐Diels–Alder Reaction: From Nitrile Activation to Functional Molecular Architectures
This Concept Article presents the evolution of the cyano‐Diels–Alder reaction from its early examples to its current development as a valuable synthetic tool for the preparation of N‐heterocycles, fused polycycles and functional chromophores, tracing the key breakthroughs that have transformed this underexplored transformation into a relevant platform ...
Giovanni Bottari
wiley +1 more source
Catalytic Asymmetric Dearomative Cyclizations of Indolyldimethanols via Umpolung Strategy. [PDF]
Wu P +5 more
europepmc +1 more source
Beszámoló a „Politikai régió – Régiópolitika” konferenciáról
Kundi Viktória
doaj +1 more source
Biobased Cyclic Enoate Monomers: Enabling Intrinsically Crystalline, Chemically Recyclable, Ultratough Polymers. [PDF]
Wang Y +7 more
europepmc +1 more source
Strain-Release Pentafluorosulfanylation of Carbonyl-Containing Disubstituted Bicyclobutanes: A Fortuitous Path to SF<sub>5</sub>-Containing Oxa[2.1.1]bicyclohexanes. [PDF]
A regio‐ and diastereoselective method for strain‐release pentafluorosulfanylation of carbonyl‐containing 1,3‐disubstituted [1.1.0]bicyclobutanes (BCBs) was developed that led to several fortuitous discoveries. For instance, the resultant SF5‐cyclobutanes (SF5‐CBs) exhibit close SF5⋯C═X contacts (X = C, N, O) and provide synthetic access to a new class
Stephens AM +9 more
europepmc +2 more sources

