Results 161 to 170 of about 18,552 (216)

Stereoselective Higher-Order [10+4]- and [10+6] Cycloadditions Between Two Highly Unsaturated and Ambiphilic π-Addends. [PDF]

open access: yesChemistry
Aminocatalytically generated isobenzofulvenes and 3‐oxidopyridinium betaines act as ambiphilic reaction partners in orbital‐symmetry‐allowed [10+4] cycloadditions or formally symmetry‐forbidden concerted thermal [10+6] cycloadditions. The reaction furnishes three cycloadducts: one [10+4] cycloadduct and two regioisomeric [10+6] cycloadducts.
Faghtmann J   +7 more
europepmc   +2 more sources

Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi   +5 more
wiley   +1 more source

The Jekyll and Hyde Nature of Tetrazoles in Polymer Science: From Intrinsic Electronic Duality to Programmable Macromolecular Function

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 36, 1 September 2026.
Tetrazoles are reframed as substitution‐programmable heterocycles rather than static functional groups in polymer chemistry. By linking electronic identity to synthetic strategy and polymer architecture, this mini‐review establishes a design framework for translating tetrazole duality into predictable macromolecular function.
Meryem S. Akdemir, Hatice Mutlu
wiley   +1 more source

Regio- and Stereoselective Deprotonation and Functionalization of Strained 1-Aza[n.1.0]bicycles. [PDF]

open access: yesJ Am Chem Soc
Xie T   +7 more
europepmc   +1 more source

Machine Learning for Synthetic Organic Chemistry: Methods, Applications, and Best Practices

open access: yesAngewandte Chemie Novit, Volume 2, Issue 3, September 2026.
Artificial intelligence (AI) and machine learning (ML) are increasingly reshaping experimental chemistry. This review maps the challenges of synthetic organic chemistry to modern digital tools that can help address them. While focusing on the practical application of ML tools in real‐world laboratory settings, we outline prerequisites, emerging ...
Niklas Hölter   +3 more
wiley   +1 more source

Cobalt-Catalyzed Migratory E-Selective Asymmetric Aza-Nozaki-Hiyama-Kishi Coupling. [PDF]

open access: yesAngew Chem Int Ed Engl
Wang Y   +7 more
europepmc   +1 more source

Hydrazone‐Type Ligands for Asymmetric Catalysis

open access: yesChemistryEurope, Volume 4, Issue 9, September 2026.
The introduction of trans 2,5‐disubstituted pyrrolidines is the key design element enabling the excellent stereocontrol exerted by hydrazone‐based N‐ligands in a variety of transition metal‐catalyzed transformations, including Diels–Alder cycloadditions, Suzuki/Hiyama/Negishi cross‐couplings, 1,2‐additions to a variety of imines and hydrazones, and ...
Esteban Matador   +4 more
wiley   +1 more source

Catalytic Asymmetric Cationic Geranyl Cyclizations. [PDF]

open access: yesJ Am Chem Soc
Luo N   +5 more
europepmc   +1 more source

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