Results 161 to 170 of about 238,995 (200)

Total neoadjuvant therapy in rectal cancer: Challenging traditions without compromising surgical safety. [PDF]

World J Gastrointest Oncol
Karmakar R, Kandalkar A, Mukundan A.
europepmc   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

The role of chemoradiotherapy after induction in locally advanced pancreatic cancer: lessons learnt from CONKO-007. [PDF]

J Gastrointest Oncol
Athanasiou C, Pandanaboyana S.
europepmc   +1 more source

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

Advanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu, Huiyuan Ma, Tinghui Zhu, Shuwei Huang, Manxi Lu, Qiong Wang, Zai‐Long Chi   +6 more
wiley   +1 more source

Clinical Efficacy Exploration of Temperature-Sensitive Embolic Agent TACE Combined with HAIC and Targeted/Immunotherapy for Unresectable Primary Liver Cancer. [PDF]

J Hepatocell Carcinoma
Chen X, Xiao H, Lan X, Du C.
europepmc   +1 more source

Approaching Scarless Wound Healing: From Passive Anti‐Fibrotic to Proactive and Programmable Pro‐Regenerative Strategies

Advanced Science, EarlyView.
This review outlines the wound healing process and factors influencing scar formation, explores how certain animals and human fetuses achieve scarless skin or tissue regeneration, and details tissue engineering material strategies employed in scarless wound dressings.
Meimei Fu, Zhuoyi Huang, Jintao Li, Yue Li, Zhou Fang, Yiwen Jiang, Keke Wu, Jinshan Guo   +7 more
wiley   +1 more source

Natural ovulation versus programmed regimens before frozen embryo transfer in ovulatory women: multicentre, randomised clinical trial.

BMJ
Wei D, Qin Y, Sun Y, Yan J, Zhao H, Guan Y, Tan J, Guo T, Wang Z, Gong F, Hao C, Ma X, Zhang C, Zhang A, Geng L, Sun M, Li X, Ling X, Lu Q, Bao H, Chao L, Huang W, Shi Q, Zhao J, Lu Y, Wu S, Zhang S, Wang J, Guo M, Sun X, Ma Y, Wu Q, Li Y, Ou X, Fang Z, Chen J, Hao G, Zhang H, Legro RS, Chen ZJ, PnROVE Study Group.   +40 more
europepmc   +1 more source

Venetoclax-Based Therapy for Early Relapse in Acute Myeloid Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report and Minireview. [PDF]

Cancer Rep (Hoboken)
Du Y, Hassani MA, Li C, Zhao Z, Liu Y, Zhang C, Yan J.   +6 more
europepmc   +1 more source

Neutrophil‐Mimetic Nanoscavengers Target the Inflammatory Microenvironment to Eliminate NETs/ROS and Immunomodulate cGAS‐STING Signaling in Septic AKI

Advanced Science, EarlyView.
Sepsis‐associated acute kidney injury is driven by oxidative stress, NETs overproduction, and dysregulated innate immunity. Here, we develop neutrophil‐mimetic nanoscavengers that integrate ROS‐scavenging Mn3O4 nanozymes with DNase‐1‐mediated NETs degradation to suppress cGAS‐STING signaling, reprogram macrophage polarization, and effectively alleviate
Zening Zhang, Chenxi Zhang, Ranran Luo, Qiuchi Wu, Pengchen Ren, Xinyu Liu, Yingying Luo, Zhongsheng Xu, Xiaojing He, Yun Liu   +9 more
wiley   +1 more source

Improved guideline adherence may not overcome evidence gaps in severe trimethoprim-sulfamethoxazole-resistant <i>Stenotrophomonas maltophilia</i> infection: a case-based perspective. [PDF]

Antimicrob Steward Healthc Epidemiol
Şahinoğlu MS, Özer Kökkızıl S, Şimşek Bozok T.   +2 more
europepmc   +1 more source