Results 41 to 50 of about 657,982 (247)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Tecnología, especialismo y sus audiencias. La «Clínica de Leucemias» del Hospital Provincial de Alicante (1953-1960) [PDF]

, 2004
La puesta en marcha de una Clínica de Leucemias en el Hospital Provincial de Alicante supuso un revulsivo para el inicio de una actividad investigadora en el marco de un proceso de institucionalización de la especialidad hematológica. El prestigio social
Ballester, Rosa, Perdiguero Gil, Enrique
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

El nou règim local general i la seva aplicació diferenciada a les diferents comunitats autònomes

Revista Catalana de Dret Públic, 2014
La recent Llei 27/2013, de 27 de desembre, de racionalització i sostenibilitat de l’Administració local (LRSAL) suscita qüestions importants i complexes des de la perspectiva de la validesa competencial de la pròpia llei i de la seva aplicació a les ...
Francisco Velasco Caballero
doaj   +1 more source

Ser y parecer en el Antiguo Régimen. Los problemas de un regidor bajito [PDF]

, 2000
El trabajo está dividido en dos partes: la primera de ellas es un pequeño relato sobre un conflicto protocolario escrito a partir de fuentes locales (Zaragoza, siglos XVIII-XIX).
Maestrojuán, F.J. (Francisco Javier)
core  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Plan de manejo ambiental para la planta de procesamiento de Brócoli que opera bajo el régimen de zona franca especial en el municipio de Ipiales - Nariño [PDF]

, 2010
La implementación y puesta en marcha de la planta de procesamiento de brócoli Alimentos Nariño bajo el régimen de zona franca permanente especial en el municipio de Ipiales, es un macro proyecto que ejercerá presión positiva y negativa sobre los tres ...
Folleco Villareal, María Fernanda, Revelo Jiménez, Victor Hugo   +1 more
core  

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Zonas de régimen aduanero especial [PDF]

, 2012
Las zonas del régimen aduanero especial están reguladas principalmente por el estatuto tributario, Decreto 2685 de 1999 y en la resolución 4240 de 2000.
Naranjo Posada, Alejandro, Zapata Montoya, Deisy Andrea   +1 more
core