Results 41 to 50 of about 65,591 (246)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Reparasie, die onbetaalde rekening van die Waarheids- en Versoeningsproses
Verbum et Ecclesia, 2000 Reparations, the unpaid account of the Truth and Reconciliation ProcessThe author contends that the final question about the contribution of the South African Truth and Reconciliation Commission will not be whether the Human Rights Violations Committee ...
P. G. J. Meiring
doaj +1 more source
L'assurance des dommages matériels au Québec et l'indemnisation directe : un régime efficace mais encore mal compris [PDF]
, 1998 Depuis vingt ans, la réparation des dommages causés aux automobiles s'effectue suivant le principe de l'indemnisation directe basée sur la faute chaque fois que deux ou plusieurs véhicules sont impliqués dans un accident.
Belleau, Claude
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
An ethical and aesthetic challenge: symbolic reparation and the construction of memory
Torture, 2018 This article concerns the Clínicas do Testemunho, a pilot project carried out in Rio de Janeiro, which was supported by the Amnesty Commission of the Brazilian Ministry of Justice and was carried out between 2013 and 2015.
Vera Vital-Brasil
doaj +1 more source
Incendies de forêts : obtenir réparation des préjudices subis
Revue Forestière Française, 2023 Les incendies très importants de forêts de l’été 2022 questionnent sur les responsabilités pénales ou civiles des auteurs de ces faits dans le cadre d’incendies criminels ou accidentels mais également sur les possibilités d’indemnisation des ...
Jacques Liagre
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Gross human rights violations and reparation under international law: approaching rehabilitation as a form of reparation [PDF]
European Journal of Psychotraumatology, 2013 The strengthening of international criminal law through an increased focus on the right to reparation and rehabilitation for victims of crimes against humanity represents an important challenge to health professionals, particularly to those in the field ...
Nora Sveaass
doaj +1 more source
Lésions iatrogènes des voies biliaires lors de la cholécystectomie laparoscopique [PDF]
, 2012 Objective: Laparoscopic cholecystectomy (LC) has become the gold standard in the treatment of symptomatic cholelithiasis. The aim of this study was to determine the frequency of occurrence and risk factors of iatrogenic bile duct injuries (IBDI) in the ...
Martin, D.
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