Results 61 to 70 of about 65,591 (246)

Implication du polymorphisme d’enzymes de métabolisation et/ou de réparation dans le suivi de travailleurs exposés au styrène, à des solvants, des pesticides ou à l’arsenic [PDF]

open access: yes, 2010
Les cancérogènes environnementaux sont convertis, par des enzymes de métabolisation dits de phase I ou de fonctionnalisation) et des enzymes de phase II ou de conjugaison), en métabolites réactifs pouvant se fixer à l’ADN.
Pfohl-Leszkowicz, Annie
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

REPARATION DES PREJUDICES SUBIS PAR UN SALARIE LICENCIE INJUSTEMENT ET REINTEGRE PAR LE TRIBUNAL DU TRAVAIL EN DROIT CONGOLAIS [PDF]

open access: yesCahiers Africains des Droits de l’Homme et de la Démocratie ainsi que du Développement Durable
Le régime de sanction en cas de licenciement injuste ne prévoit pas une indemnisation du salarié lorsque ce dernier est réintégré par le tribunal. Cependant, la décision de réintégration ne peut être prononcée par le tribunal qu’à l’issue d’une procédure
Léon BALEKELAYI MULUMBA
doaj  

Reparation a morale justice for Africa: the Benin (Nigeria) in perspective

open access: yesVestnik RUDN. International Relations, 2017
The paper offered a review of Africa’s moral call for reparation. It emphasized among other things that the continued underdevelopment and marginalization of the African continent today, is not unconnected with the trilogy of slavery, imperialism and ...
Stephen Osaherumwen Idahosa   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Strategic Role of Lembaga Adat Negeri in the Fulfilment of Victims’ Rights to Reparation in Post-Conflict Ambon

open access: yesUdayana Journal of Law and Culture, 2017
This article demonstrates the strategic position of Lembaga Adat Negeri in the fulfilment of the long-neglected right to reparation of victims in post-conflict Ambon.
Trihoni Nalesti Dewi   +2 more
doaj   +1 more source

フランス ノ ケイジ ワカイ 1 [PDF]

open access: yes, 2004

Shimaoka, Mana   +2 more
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Reparations of the horse? Algorithmic reparation and overspecialized remedies

open access: yesBig Data & Society
In his seminal article, “Cyberspace and the Law of the Horse,” Frank Easterbrook criticized the scholarly trend of developing overspecialized legal approaches to emerging technologies.
Colin Doyle   +5 more
doaj   +1 more source

Reparative approach Towards victims of armed Conflict: global experiences and lessons for india

open access: yesBRICS Law Journal, 2019
In recent years, relentless efforts have been made worldwide for repairing the past harms done to victims of armed conflict. There has been a paradigm shift in international human rights law to addressing the victims’ need for reparation rather than ...
B. Sonowal, D. Dube
doaj   +1 more source

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