Results 91 to 100 of about 2,999,114 (251)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Violence politique, insécurité et résistance : le cas des femmes honduriennes après le coup d’État de 2009

open access: yesCriminologie, 2012
Le présent article s’appuie sur une enquête qualitative qui porte sur les expériences de 48 femmes honduriennes à la suite du coup d’État qui a frappé leur pays le 28 juin 2009. Il souligne en particulier leurs expériences de la répression étatique et de
Christine Gervais, Jennifer Kilty
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Pulmonary hypertension in infants with congenital heart defects: are leukotrienes involved?

open access: yesMediators of Inflammation, 1997
The circulating levels of leukotriene E4 in infants with congenital heart defects, increased pulmonary blood flow and pulmonary arterial hypertension, were determined and compared with infants with decreased pulmonary blood flow (Tetralogy of Fallot ...
A. Serraf   +5 more
doaj   +1 more source

Existence chez la pomme de terre de résistance induite vis-à-vis de Globodera rostochiensis [PDF]

open access: yes, 1994
Le mécanisme de résistance à #G. rostochiensis$ Ro1/4 de deux génotypes ex-#vernei$ de pomme de terre et leurs parents est étudié selon diverses méthodologies.
Balandras, C.   +2 more
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Glycoconjugate secretion in human airways in vitro: effects of epithelium removal

open access: yesMediators of Inflammation, 1998
The aim of this study was to examine glycoconjugate secretion in human airways with and without an epithelium. Glycoconjugate release in supernatants derived from human airways in vitro was determined using an ELISA assay with an anti-human mucin ...
H. Sossé-Alaoui   +5 more
doaj   +1 more source

In Memoriam / Décès [PDF]

open access: yes, 2020
John GamerRobert S. Gordon.A.M. Keppel-JonesR.

core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Premiers résultats sur le déterminisme de la résistance du cotonnier à la nouvelle race de Xanthomonas campestris pv. malvacearum [PDF]

open access: yes, 1987
La résistance à la nouvelle race de X. campestris pv. malvacearum entraine la résistance aux autres races. L'inoculation artificielle de la seule nouvelle race est suffisante pour la recherche de variétés de cotonnier ...
Follin, Jean-Claude, Girardot, Benoit
core  

Home - About - Disclaimer - Privacy