Results 71 to 80 of about 3,188,385 (233)
Aides à la Recherche de la Fondation de la Résistance
, 2013 LA FONDATION DE LA RÉSISTANCE PROPOSE DEUX MODALITÉS D'AIDE À LA RECHERCHE 1) Offre d'un poste de doctorant-chercheur (ANNÉE UNIVERSITAIRE 2013-2014) La Fondation de la Résistance propose un contrat à durée déterminée d'une durée d'un an (année ...
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Répression et Résistance : bilan de deux journées d'études (Rennes, Dijon)
, 2011 Au cours de l'année 2010-2011, le Centre d’histoire et de recherches sur la Résistance a organisé deux journées d’études complémentaires sur le thème « Répression et Résistance ».
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
América, 2015 Un an et demi après sa libération le 2 juillet 2008, l’ex-otage Ingrid Betancourt publie Même le silence a une fin, récit de son enfermement dans les mains des Fuerzas Armadas Revolucionarias Colombianas (FARC).Pour analyser l’expérience de l’enfermement
Carmen Medrano-Ollivier
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Publication : "Histoire de la Résistance : nouveaux chercheurs, nouveaux apports"
, 2011 La revue Guerres mondiales et conflits contemporains (Presses universitaires de France) publie dans son dernier numéro un dossier "Histoire de la Résistance : nouveaux chercheurs, nouveaux apports".
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source