Results 91 to 100 of about 3,095,409 (252)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Triaxial compression tests on a crushable sand in dry and wet conditions [PDF]

open access: yes, 2015
A calcareous sand from the Persian Gulf is subjected to a series of dry and fully drained saturated triaxial shear tests. The samples are prepared at relative densities of 65% and either left dry or saturated. They are consolidated to confining pressures
Haegeman, Wim, Van Impe, PO, Wils, L
core   +1 more source

Les résistantes, perspectives de recherche [PDF]

open access: yes, 1961
Existe-t-il une résistance féminine spécifique, distincte de celle des hommes ? L'idéal de la mère épouse au foyer qui s'est imposé des années 1930 aux années 1950 a-t-il été favorable ou défavorable à l'engagement des femmes dans la Résistance ?
Andrieu, Claire
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Les femmes détenues d’Unité 9 : entre espace fictionnel et réalité

open access: yesCriminologie, 2016
Dans cet article, nous nous penchons sur Unité 9, une télésérie québécoise portant sur l’univers carcéral au féminin, pour dresser un parallèle entre celle-ci et l’incarcération des femmes de ressort fédéral.
Sophie Cousineau, Sylvie Frigon
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

First record of three species of "Pythium" from Moroccan waters [PDF]

open access: yes, 2007
First record of three species of Pythium from Moroccan waters. Species of Pythium, including P.torulosum, P.catenulatum and P. "Group F", isolated from dam near Rabat city (capital of Morocco) in northern Africa, are described.
Ben Abdellah, Samira   +5 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Pulmonary hypertension in infants with congenital heart defects: are leukotrienes involved?

open access: yesMediators of Inflammation, 1997
The circulating levels of leukotriene E4 in infants with congenital heart defects, increased pulmonary blood flow and pulmonary arterial hypertension, were determined and compared with infants with decreased pulmonary blood flow (Tetralogy of Fallot ...
A. Serraf   +5 more
doaj   +1 more source

Lutte contre la maladie du jaunissement mortel au Ghana : research of resistant varieties among thirty coconut varieties (Cocos nucisfera L.) [PDF]

open access: yes, 2008
Les maladies du jaunissement mortel qui dévastent les cocoteraies sont connues en Amérique Latine et en Afrique. Au Ghana, la maladie est apparue en 1932 dans la zone du Cap Saint Paul. Elle s'est étendue à la Western région qui représente près de 90% de
Allou, Kouassi   +4 more
core  

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