Results 61 to 70 of about 3,025,660 (244)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Un fonds Germaine Tillion exceptionnel au Musée de la Résistance et de la Déportation de Besançon
, 2014 Le fonds Germaine Tillion au Musée de la Résistance et de la Déportation. Le transfert prochain au Panthéon des cendres de Germaine Tillion, figure incontournable de la Résistance française, a été annoncé ce 21 février. Le Musée de la Résistance et de la
ch2r
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
América, 2015 Un an et demi après sa libération le 2 juillet 2008, l’ex-otage Ingrid Betancourt publie Même le silence a une fin, récit de son enfermement dans les mains des Fuerzas Armadas Revolucionarias Colombianas (FARC).Pour analyser l’expérience de l’enfermement
Carmen Medrano-Ollivier
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Cahiers d’histoire, 2015 Face à la domination coloniale au Viet Nam, les confucéens ont eu un apport significatif à l’esprit de résistance et au patriotisme. En particulier, la politique de la « marge », notamment les groupes stigmatisés par la mémoire historique comme les ...
Trinh Van Thao
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Aides à la Recherche de la Fondation de la Résistance
, 2013 LA FONDATION DE LA RÉSISTANCE PROPOSE DEUX MODALITÉS D'AIDE À LA RECHERCHE 1) Offre d'un poste de doctorant-chercheur (ANNÉE UNIVERSITAIRE 2013-2014) La Fondation de la Résistance propose un contrat à durée déterminée d'une durée d'un an (année ...
ch2r
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