Résistance du Cytomégalovirus aux antiviraux
International audienceLa résistance du cytomégalovirus aux antiviraux est un véritable problème en transplantation, mais aussi chez d'autres patients immunodéprimés, conduisant parfois à l'impasse thérapeutique.
Alain, Sophie +2 more
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Recent Outbreaks, Resistance Trends, and Control Measures in <i>Candida auris</i> and <i>Candida glabrata</i> Infections. [PDF]
Raeisi S, Madhavan P, Adisuri DS.
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Entre brouillard et cicatrices : le corps-territoire comme lieu de résistance
Claudia Bernal
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Uncovering the genetic basis of crown rust resistance in a northern-by-southern oat biparental population. [PDF]
Sapkota S +7 more
europepmc +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
HIV-1 Resistance to Dolutegravir in Benin: The Need to Improve and Strengthen Therapeutic Patient Education Strategies to Achieve the Third Objective 95 of UNAIDS 95-95-95 Target. [PDF]
Tchiakpe E +4 more
europepmc +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Comparative genomic analysis of RNA-binding proteins across some drug resistant and sensitive Staphylococcus aureus. [PDF]
Awad MM, Osman YA, Abdelmoteleb M.
europepmc +1 more source

