Results 141 to 150 of about 3,188,385 (233)

Metagenomic Characterisation of Antibiotic Resistance in Anaerobic Digesters and Their Implications for Environmental Health. [PDF]

Environ Microbiol Rep
Olasupo OA, Olaniyan OP, Akinde SB, Adesoye AA, Ajadi FA, Obire O, Oladipo EK, Sule WF, Oyinloye OE, Salami AA, Fajoyegbe ES, Ajani AJ, Ojo O.   +12 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Ana Lucia Araujo. 2021. Museums and Atlantic Slavery

Culture & Musées
Caroline Creton
doaj   +1 more source

Antibiotic Resistance Trends and Prescribing Patterns in Pediatric Non-Typhoidal <i>Salmonella</i> Enteritis: A 10-Year Single-Centre Retrospective Study. [PDF]

Infect Drug Resist
Liao X, Lu J, Yang R, Wu L, Wang C.
europepmc   +1 more source

Les résistances en Europe

, 2011
Arte diffuse à partir du mercredi 12 octobre une série documentaire consacrée aux résistances européennes : "Les Combattants de l'ombre". Ce documentaire semble s'inscrire dans le prolongement des quelques travaux de recherche menés depuis les années ...
ch2r
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Architected conductive networks enabling tunable pressure sensitivity in stretchable sensor arrays for intelligent tactile perception. [PDF]

Microsyst Nanoeng
Zhu J, Zhang H, Bian Y, Yuan Q, Shou J, Chen R, Chen M, Zhuang L, Wang P, Wang X.   +9 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Experimental Evolution of Reduced Susceptibility to Artemether-Lumefantrine in <i>Plasmodium berghei</i> Following Serial Drug Pressure. [PDF]

J Parasitol Res
Njoroge SM, Kimani SK, Ngonjo TW, Olunga MS, Seng Ete Wambua J, Waithera MW, Wawa HY, Ng Ang A Waweru J.   +7 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source