Results 51 to 60 of about 3,502,443 (305)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
LFM: An R package for laplace factor model
SoftwareXThe Laplace Factor Model (LFM) is a valuable mathematical tool used in statistics, machine learning, and data analysis. It uses the Laplace distribution to capture data sparsity and uncertainty, effectively handling complex, large-scale data.
Siqi Liu, Guangbao Guo
doaj +1 more source
Sarăcia - factor favorizant al delicvenţei juvenile în R. Moldova [PDF]
Revista Institutului Naţional de Justiţie, 2014 Poverty - the favorable factor of the juvenile delinquency in the Republic of Moldova. It is diffi cult to fi nd a concise, detailed and non-technical discussion about the reasons of the juvenile delinquency.
Plămădeală Alina
doaj
3-(4-Chlorophenylsulfonyl)-8-methyl-1,3-diazaspiro[4.5]decane-2,4-dione [PDF]
, 2009 In the title compound, C15H17ClN2O4S, the atoms in the hydantoin ring are coplanar (r.m.s. deviation = 0.006 Å). The crystal structure is stabilized by intermolecular N-H...O hydrogen bonds which link the molecules into centrosymmetric dimers.
M. Kalim Kashif +15 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait +23 more
wiley +1 more source
TFM: An R package for truncated factor model
SoftwareXThe Truncated Factor Model (TFM) is a statistical model for analyzing high-dimensional truncated data, leveraging sparsity and online learning to extract common factors.
Beibei Wu, Guangbao Guo
doaj +1 more source
Phthalazin-1(2H)-one–picric acid (1/1) [PDF]
, 2007 The geometric parameters of the title compound, C8H6N2O·C6H3N3O7, are in the usual ranges. The three nitro groups are almost coplanar with the aromatic picrate ring [dihedral angles 10.2 (2)°, 7.62 (16) and 8.08 (17)°].
Bolte, Michael +4 more
core +4 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
R Factor Proteins Synthesized in Escherichia coli Minicells: Membrane-Associated R Factor Proteins [PDF]
Journal of Bacteriology, 1974 R factor proteins are synthesized in R factor-containing Escherichia coli minicells. Half of this protein remained associated with the minicell membrane upon lysis of the minicells. Over 90% of the membrane-associated protein was extracted by sodium lauryl sarcosinate, suggesting a location of these proteins in the ...
S B, Levy, L, McMurry, E, Palmer
openaire +2 more sources
3-(4-Bromophenylsulfonyl)-8-methyl-1,3-diazaspiro[4.5]decane-2,4-dione [PDF]
, 2009 The crystal structure of the title compound, C15H17BrN2O4S, is stabilized by intermolecular N-H...O hydrogen bonds which link the molecules into centrosymmetric dimers.
M. Kalim Kashif +15 more
core +1 more source