Results 151 to 160 of about 27,605,430 (309)

Integrated Operational Modeling of the Harmful Algal Blooms(HABs) Using R

open access: yes, 2019
Harmful algal blooms(HABs) are critical issues on the coastal ocean. Government agencies and ocean scientists are struggling to reduce the damage of coastal aquaculture by HABs.
강돈혁   +3 more
core  

Knowledge Distillation‐Based Zero‐Shot Learning for Process Fault Diagnosis

open access: yesAdvanced Intelligent Systems
Data‐driven deep learning is effective in diagnosing known faults, but not so well when new or unknown faults occur. With unknown faults as a zero‐shot learning problem, this article proposes a method for detecting and isolating unknown faults based on ...
Yi Liu, Jiajun Huang, Mingwei Jia
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Electro‐Driven Multi‐Enzymatic Cascade Conversion of CO2 to Ethylene Glycol in Nano‐Reactor

open access: yesAdvanced Science
Multi‐enzymatic cascade reaction provides a new avenue for C─C coupling directly from CO2 under mild conditions. In this study, a new pathway with four enzymes including formate dehydrogenase (PaFDH), formaldehyde dehydrogenase (BmFADH), glycolaldehyde ...
Likun Luan   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Process Biochem.

open access: yes, 1999
Air pressure amplitude serves as a critical control parameter of periodic pressure solid state fermentation process. Effects of different air pressure amplitudes on cellulase production by Trichoderma viride-SL were investigated. Experiments were carried
Sun, T, Li, ZH, Liu, BH, Liu, DM
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy