Results 1 to 10 of about 14,284,870 (172)

Molecular detection of Rickettsia typhi in cats and fleas. [PDF]

PLoS ONE, 2013
BACKGROUND: Rickettsiatyphi is the etiological agent of murine typhus (MT), a disease transmitted by two cycles: rat-flea-rat, and peridomestic cycle. Murine typhus is often misdiagnosed and underreported.
Maria Mercedes Nogueras, Immaculada Pons, Ana Ortuño, Jaime Miret, Julia Pla, Joaquim Castellà, Ferran Segura   +6 more
doaj   +3 more sources

Simultaneous serological assessment of four zoonotic rickettsiae among dogs near the United States-Mexico border. [PDF]

PLoS Neglected Tropical Diseases
Obligately intracellular rickettsiae cause a broad spectrum of disease in humans and animals, ranging from mild illness to life-threatening infections. Multiple species co-circulate along the southern United States of America-northern Mexico border, yet ...
Francesca Rubino, Sarah A Hamer, Andres M López-Pérez, Samantha Schuchman, Kailyn Lozano, Alexandra Saffold, Mario A Rodríguez-Pérez, Nadia A Fernández-Santos, Janet Foley   +8 more
doaj   +2 more sources

A repetitive nucleotide insertion in the rplV gene is associated with in vitro resistance to azithromycin in Rickettsia typhi. [PDF]

PLoS Neglected Tropical Diseases
BackgroundMurine typhus, caused by Rickettsia typhi, is a treatable febrile illness in Laos, where azithromycin treatment failure has been reported. Antibiotic susceptibility testing for Rickettsia spp. is challenging due to absence of resistant strains.
Weerawat Phuklia, Kiattawee Chowongkomon, Kaisone Padith, Koukeo Phommasone, Mayfong Mayxay, Allen L Richards, Elizabeth M Batty, Matthew T Robinson, Paul N Newton, Nicholas J White, Nicholas P J Day, Elizabeth A Ashley   +11 more
doaj   +2 more sources

Rickettsia typhi seroprevalence among patients with unexplained acute fever at the Sourô Sanou University Hospital Center (SSUHC), Burkina Faso [PDF]

BMC Infectious Diseases
Background This study aimed to evaluate the seroprevalence of anti-IgG antibodies against Rickettsia typhi among patients with unexplained acute fever (UAF) at the Sourô Sanou University Hospital (CHUSS) in Bobo-Dioulasso, Burkina Faso.
Muhigwa Merci, Kaboré Odilon Dieudonné, Gouba Nina, Da Frédéric Sylvère, Thiombiano P. F. Roseline Diane, Zoungrana Jacques, Poda Armel, Ouedraogo Abdoul-Salam   +7 more
doaj   +2 more sources

Targeting surface cell antigen 2 increases sensitivity of Rickettsia typhi detection. [PDF]

PLoS Neglected Tropical Diseases
BackgroundMurine typhus is a flea-borne disease caused by Rickettsia typhi that typically presents as an acute febrile illness. The diagnosis is often missed, leading to delays in appropriate treatment. A qPCR targeting a single gene (ompB) for R.
Weerawat Phuklia, Kaisone Padith, Koukeo Phommasone, Vilada Chansamouth, Mayfong Mayxay, Susath Vongphachanh, Paul N Newton, Matthew T Robinson, Elizabeth A Ashley   +8 more
doaj   +2 more sources

Autophagy facilitates intracellular survival of pathogenic rickettsiae in macrophages via evasion of autophagosomal maturation and reduction of microbicidal pro-inflammatory IL-1 cytokine responses

Microbiology Spectrum, 2023
The genus Rickettsia is comprised of obligate intracellular bacterial parasites of a wide range of arthropod and vertebrate hosts. Some Rickettsia species (spp.) are responsible for serious human diseases globally.
Oliver H. Voss, Hodalis Gaytan, Saif Ullah, Mohammad Sadik, Imran Moin, M. Sayeedur Rahman, Abdu F. Azad   +6 more
doaj   +1 more source

Liver Necrosis and Lethal Systemic Inflammation in a Murine Model of Rickettsia typhi Infection: Role of Neutrophils, Macrophages and NK Cells. [PDF]

PLoS Neglected Tropical Diseases, 2016
Rickettsia (R.) typhi is the causative agent of endemic typhus, an emerging febrile disease that is associated with complications such as pneumonia, encephalitis and liver dysfunction.
Stefanie Papp, Kristin Moderzynski, Jessica Rauch, Liza Heine, Svenja Kuehl, Ulricke Richardt, Heidelinde Mueller, Bernhard Fleischer, Anke Osterloh   +8 more
doaj   +1 more source

Cytotoxic effector functions of T cells are not required for protective immunity against fatal Rickettsia typhi infection in a murine model of infection: Role of TH1 and TH17 cytokines in protection and pathology. [PDF]

PLoS Neglected Tropical Diseases, 2017
Endemic typhus caused by Rickettsia (R.) typhi is an emerging febrile disease that can be fatal due to multiple organ pathology. Here we analyzed the requirements for protection against R. typhi by T cells in the CB17 SCID model of infection. BALB/c wild-
Kristin Moderzynski, Liza Heine, Jessica Rauch, Stefanie Papp, Svenja Kuehl, Ulricke Richardt, Bernhard Fleischer, Anke Osterloh   +7 more
doaj   +1 more source

Seroprevalence of Orientia tsutsugamushi and Rickettsia typhi in water buffaloes (Bubalus bubalis) from Southern Thailand [PDF]

Veterinary World, 2023
Background and Aim: Scrub typhus and murine typhus are globally distributed zoonoses caused by the intracellular Gram-negative bacteria Orientia tsutsugamushi and Rickettsia typhi, respectively.
Decha Pangjai, Phirabhat Saengsawang, Kamchai Kidsin, Ngamchit Choongkittaworn, Yukio Morita, Sumalee Boonmar   +5 more
doaj   +1 more source

Serosurvey of IgG Antibodies against Bartonella henselae and Rickettsia typhi in the Population of Attica, Greece

Tropical Medicine and Infectious Disease, 2020
Rickettsia typhi and Bartonella henselae are the causative agents of murine typhus and cat-scratch disease, respectively. A small-scale survey (N = 202) was conducted in the Attica region, Greece, for determining the prevalence rates of IgG antibodies ...
Georgios Dougas, Maria Mavrouli, Athanassios Tsakris, Charalambos Billinis, Joseph Papaparaskevas   +4 more
doaj   +1 more source