Results 191 to 200 of about 117,798 (282)

EphB1 Receptor Blockade Augments Morphine Antinociception via Inhibiting GRK2‐Mediated µ‐Opioid Receptor Internalization

Advanced Science, EarlyView.
Administration of opioids activates ephrinB2‐EphB1 receptor signaling. Activated EphB1 receptors induce GRK2‐mediated phosphorylation of MOR at Ser375, which initiates the internalization of MOR and reduces opioid antinociception at the behavioral level. ABSTRACT Opioids are the primary treatment for severe pain in clinical practice.
Bo Peng, Xiaqing Lin, Hongyu Yao, Cheng Li, Huabao Liao, Yuexin Liu, Boxu Cao, Xue‑Jun Song   +7 more
wiley   +1 more source

The consequences of host heterogeneity for parasite transmission depend on how host infectiousness is determined. [PDF]

J Anim Ecol
Cohen JA, Dean AD, Viney M, Fenton A.
europepmc   +1 more source

Interfacial Asymmetry and Surface Roughness Enhanced Topological‐Hall‐Like Transport in SRO/BTO/SRO Trilayers

Advanced Science, EarlyView.
Trilayer oxide architecture introduces interfacial asymmetry and surface roughness in SRO/BTO/SRO heterostructures, creating a locally modulated polar and magnetic landscape. This design enhances the topological‐Hall‐like response, achieving a broad 5–90 K stability window and a maximum ρTHE of 0.8 µΩ cm, demonstrating an effective route to amplify ...
Sagar E. Shirsath, Yunlong Sun, Xichao Zhang, Ji Zhang, Akash V. Fulari, Zizheng Song, Yee Yan Tay, Yin Yao, Zibin Chen, Sean Li, Xiaoxi Liu, Danyang Wang   +11 more
wiley   +1 more source

Conversion Surgery for Advanced Gastric Cancer According to First-Line Treatment Strategy: A Single-Center Experience with a Focused Review of the Literature. [PDF]

Cancers (Basel)
Kinoshita J, Doden K, Hayashi K, Matsui R, Saito H, Watanabe M, Tsuji T, Yamamoto D, Inaki N.   +8 more
europepmc   +1 more source

Lactate‐H3K18la‐RPL11 Axis Drives Gemcitabine Resistance in Pancreatic Cancer by Integrating Protein Synthesis and DNA Damage Repair

Advanced Science, EarlyView.
A lactate‐H3K18la epigenetic axis upregulates RPL11 to drive gemcitabine resistance in pancreatic cancer. RPL11 orchestrates chemoresistance through a dual, compartmentalized role: enhancing cytoplasmic protein synthesis via EEF1A1 stabilization and promoting nuclear DNA damage repair by co‐activating PARP14, thus ensuring robust cell survival ...
Lijun Zhao, Jianzhong Cao, Wenyue Liu, Xuyun Li, Haolin Zhang, Xiaofang Zhang, Shiyang Shi, Huilong Yin, Junjie Li, Angang Yang, Rui Zhang   +10 more
wiley   +1 more source

Nonlinear Strain Engineering via Meta-Material Substrates for Flexible Sensors With Simultaneously Enhanced Sensitivity and Wide Sensing Range. [PDF]

Glob Chall
Lee G, Kim SW, Choi YW.
europepmc   +1 more source

The Influence of Residual Ion Drift During Programming of Chip‐Integrated Nanoscale HfO2‐Based Memristive Devices

Advanced Electronic Materials, EarlyView.
1T1R‐arrays combining filamentary‐type memristors and CMOS transistors offer great potential for energy‐efficient analog hardware accelerators. Here, transient SET analysis of nanoscale HfO2 memristors integrated on 180 nm CMOS wafers is discussed.
Oliver Artner, Felix Cüppers, Seokki Son, Yang Chen, Xiaohua Liu, Christopher Bengel, Dennis Nielinger, André Zambanini, Stefan Wiefels, Stephan Menzel, Regina Dittmann, Susanne Hoffmann‐Eifert   +11 more
wiley   +1 more source

ASO Author Reflections: R0 Resection Should Not Be Dismissed in Node-Positive Pancreatic Ductal Adenocarcinoma. [PDF]

Ann Surg Oncol
Bonomi AM, Granieri S, Montorsi RM, Gjoni E, Busch OR, Vidal-Itriago AA, Erdmann JI, Besselink MG.   +7 more
europepmc   +1 more source

R0 and the exponential growth of a pandemic

Freakonometrics, 2020
openaire   +2 more sources

Tuning Local Modulus at Liquid Metal‐Polymer Interfaces Regulates Electrocaloric Effect in Ferroelectric Nanocomposites

Advanced Electronic Materials, EarlyView.
Liquid metal nanoparticles create mechanically compliant polymer interfaces that facilitate reversible dipolar reorientation under electric fields, whereas rigid interfaces impose stronger local constraints. This soft–rigid interface comparison reveals local interfacial modulus as a key parameter for tuning electrocaloric entropy change in ...
Tian Yao, Shanyu Zheng, Binzhou Sun, Zhenhua Ma, Feiyu Zhang, Lu Yu, Qiang Li, Ruhong Luo, Feihong Du, Yifan Zhao, Yezhan Lin, Chunyu Wang, Xin Chen, Shi‐Yang Tang, Tiannan Yang, Xiaoshi Qian   +15 more
wiley   +1 more source