Results 1 to 10 of about 14,818 (216)

Polyarginine Peptide R11–Actin Interaction Induces a Domino Effect on Cytoskeleton Remodeling to Suppress Bladder Cancer Metastasis [PDF]

Research
Cytoskeletal remodeling, particularly actin dynamics, is a central driver of tumor metastasis. However, actin-targeting agents have faced major translational barriers due to poor specificity and the absence of defined druggable sites.
Zhenghong Liu, Chuanzan Zhou, Wentao Xu, Dahong Zhang, Bin Zheng, Facai Zhang, Xiaowen Qin, Heng Wang, Yixuan Mou, Yang Liu, Haichang Li, Jing Quan, Li Sun, Yiyang Chen, Chenkai Wang, Xuanyi Zhou, Xinyi Chen, Hong Tang, Dingyi Liu, Wenyan Zuo, Dechao Feng, Pu Zhang, Qi Zhang   +22 more
doaj   +2 more sources

Intravesical delivery of mucoadhesive and tumor-selective-penetrating nanozymes for enhancing the PDT of bladder cancer [PDF]

Journal of Nanobiotechnology
Intravesical photodynamic therapy (PDT) emerges as a promising modality for bladder cancer treatment, yet its efficacy is often curtailed by weak muco-adhesion, poor muco-penetration, low tumor-targeting and intra-tumoral oxygen scarcity.
Yang Liu, Wentao Xu, Xiaowen Qin, Jiajia Zheng, Bin Zheng, Li Sun, Wenyan Zuo, Dingyi Liu, Zhenghong Liu, Yixuan Mou, Heng Wang, Qi Zhang, Jun Chen, Pu Zhang, Dahong Zhang   +14 more
doaj   +2 more sources

Exoproteome Analysis of the Seaweed Pathogen Nautella italica R11 Reveals Temperature-Dependent Regulation of RTX-Like Proteins

Frontiers in Microbiology, 2017
Climate fluctuations have been linked to an increased prevalence of disease in seaweeds, including the red alga Delisea pulchra, which is susceptible to a bleaching disease caused by the bacterium Nautella italica R11 under elevated seawater temperatures.
Melissa Gardiner, Adam M. Bournazos, Claudia Maturana-Martinez, Ling Zhong, Suhelen Egan   +4 more
doaj   +2 more sources

VarR controls colonization and virulence in the marine macroalgal pathogen Nautella italica R11 [PDF]

Frontiers in Microbiology, 2015
There is increasing evidence to suggest that macroalgae (seaweeds) are susceptible to infectious disease. However, to date, little is known about the mechanisms that facilitate the colonization and virulence of microbial seaweed pathogens. One well-described example of a seaweed disease is the bleaching of the red alga Delisea pulchra, which can be ...
Gardiner, Melissa, Fernandes, Neil D., Nowakowski, Dennis, Raftery, Mark, Kjelleberg, Staffan, Zhong, Ling, Thomas, Torsten, Egan, Suhelen   +7 more
openaire   +5 more sources

Turbulent flow of freon R11 hydrate slurry

Journal of Petroleum Science and Engineering, 2010
A set of hydrate slurry flow experiments has been conducted in a laboratory scale low-pressure flow loop. The dependence of turbulent slurry flow on the hydrate volume fraction has been studied. The slurry is shown to behave as a non-Newtonian fluid and the apparent viscosity is determined as a function of the concentration of hydrate particles.
B.V. Balakin, H. Pedersen, Z. Kilinc, A.C. Hoffmann, P. Kosinski, S. Høiland   +5 more
openaire   +2 more sources

R11 modified tumor cell membrane nanovesicle-camouflaged nanoparticles with enhanced targeting and mucus-penetrating efficiency for intravesical chemotherapy for bladder cancer.

Journal of Controlled Release, 2022
Intravesical chemotherapy is generally used in the clinic for treating bladder cancer (BCa), but its efficacy is limited due to the permeation barrier and side effects caused by the off-targeting of normal urothelial cells.
Bin Zheng, Zhenghong Liu, He Wang, Li Sun, Wing-Fu Lai, Haibao Zhang, Jinxue Wang, Yang Liu, Xiaowen Qin, Xiaolong Qi, Shuai Wang, Youqing Shen, Pu Zhang, Da-hong Zhang   +13 more
semanticscholar   +1 more source

Effects of dietary Lactobacillus reuteri on growth performance, nutrient retention, gut health and microbiota of the Nile tilapia (Oreochromis niloticus)

Aquaculture Reports, 2022
The current study aimed to evaluate the effects of Lactobacillus reuteri as a dietary supplement on growth performance, nutrient retention, digestive enzyme activities, intestinal morphology, expression of intestinal tight junction (TJ) proteins and ...
Wei Li, Xinzhi Huang, Xunzheng Lu, Biao Jiang, Chun Liu, Yanhua Huang, Youlu Su   +6 more
doaj   +1 more source

Map and sequence-based chromosome walking towards cloning of the male fertility restoration gene Rf5 linked to R11 in sunflower

Scientific Reports, 2021
The nuclear fertility restorer gene Rf5 in HA-R9, originating from the wild sunflower species Helianthus annuus , is able to restore the widely used PET1 cytoplasmic male sterility in sunflowers.
G. Ma, Y. Long, Q. Song, Z. Talukder, M. Shamimuzzaman, L. Qi   +5 more
semanticscholar   +1 more source

XtalOpt version r11: An open-source evolutionary algorithm for crystal structure prediction

Computer Physics Communications, 2018
Patrick Avery, Zackary Falls, Eva Zurek
openaire   +3 more sources

Genomes and virulence factors of novel bacterial pathogens causing bleaching disease in the marine red alga Delisea pulchra. [PDF]

PLoS ONE, 2011
Nautella sp. R11, a member of the marine Roseobacter clade, causes a bleaching disease in the temperate-marine red macroalga, Delisea pulchra. To begin to elucidate the molecular mechanisms underpinning the ability of Nautella sp. R11 to colonize, invade
Neil Fernandes, Rebecca J Case, Sharon R Longford, Mohammad R Seyedsayamdost, Peter D Steinberg, Staffan Kjelleberg, Torsten Thomas   +6 more
doaj   +1 more source