Results 11 to 20 of about 145,018 (217)

Polyarginine Peptide R11–Actin Interaction Induces a Domino Effect on Cytoskeleton Remodeling to Suppress Bladder Cancer Metastasis [PDF]

Research
Cytoskeletal remodeling, particularly actin dynamics, is a central driver of tumor metastasis. However, actin-targeting agents have faced major translational barriers due to poor specificity and the absence of defined druggable sites.
Zhenghong Liu, Chuanzan Zhou, Wentao Xu, Dahong Zhang, Bin Zheng, Facai Zhang, Xiaowen Qin, Heng Wang, Yixuan Mou, Yang Liu, Haichang Li, Jing Quan, Li Sun, Yiyang Chen, Chenkai Wang, Xuanyi Zhou, Xinyi Chen, Hong Tang, Dingyi Liu, Wenyan Zuo, Dechao Feng, Pu Zhang, Qi Zhang   +22 more
doaj   +2 more sources

Intravesical delivery of mucoadhesive and tumor-selective-penetrating nanozymes for enhancing the PDT of bladder cancer [PDF]

Journal of Nanobiotechnology
Intravesical photodynamic therapy (PDT) emerges as a promising modality for bladder cancer treatment, yet its efficacy is often curtailed by weak muco-adhesion, poor muco-penetration, low tumor-targeting and intra-tumoral oxygen scarcity.
Yang Liu, Wentao Xu, Xiaowen Qin, Jiajia Zheng, Bin Zheng, Li Sun, Wenyan Zuo, Dingyi Liu, Zhenghong Liu, Yixuan Mou, Heng Wang, Qi Zhang, Jun Chen, Pu Zhang, Dahong Zhang   +14 more
doaj   +2 more sources

Effects of dietary Lactobacillus reuteri on growth performance, nutrient retention, gut health and microbiota of the Nile tilapia (Oreochromis niloticus)

Aquaculture Reports, 2022
The current study aimed to evaluate the effects of Lactobacillus reuteri as a dietary supplement on growth performance, nutrient retention, digestive enzyme activities, intestinal morphology, expression of intestinal tight junction (TJ) proteins and ...
Wei Li, Xinzhi Huang, Xunzheng Lu, Biao Jiang, Chun Liu, Yanhua Huang, Youlu Su   +6 more
doaj   +1 more source

Genomes and virulence factors of novel bacterial pathogens causing bleaching disease in the marine red alga Delisea pulchra. [PDF]

PLoS ONE, 2011
Nautella sp. R11, a member of the marine Roseobacter clade, causes a bleaching disease in the temperate-marine red macroalga, Delisea pulchra. To begin to elucidate the molecular mechanisms underpinning the ability of Nautella sp. R11 to colonize, invade
Neil Fernandes, Rebecca J Case, Sharon R Longford, Mohammad R Seyedsayamdost, Peter D Steinberg, Staffan Kjelleberg, Torsten Thomas   +6 more
doaj   +1 more source

Radiographic examination of keel bone damage in living laying hens of different strains kept in two housing systems. [PDF]

PLoS ONE, 2018
A high prevalence of deviations and fractures of the keel bone is a widespread welfare problem in laying hens. The aim of this study was to experimentally investigate this multifactorial problem throughout the laying period and to compare the prevalence ...
Beryl Katharina Eusemann, Ulrich Baulain, Lars Schrader, Christa Thöne-Reineke, Antonia Patt, Stefanie Petow   +5 more
doaj   +1 more source

Smaller brains in laying hens: New insights into the influence of pure breeding and housing conditions on brain size and brain composition

Poultry Science, 2020
During domestication, many different chicken breeds have been developed that show many alterations compared with their wild ancestors and large variability in parameters such as body size, coloring, behavior, and even brain morphology.
Julia Mehlhorn, Stefanie Petow
doaj   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights. [PDF]

Adv Healthc Mater
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Lu Z, Yang W, Hong Y, Qiao Y, Liang C.
europepmc   +2 more sources

Comparative study on filtration effect of powdered activated carbon and activated carbon fiberboard on strong-flavor Baijiu [PDF]

Zhongguo niangzao
In this study, the filtration performance of activated carbon fiberboard (AKS1, AKS2, AKS4, R11, R33, R54) and powdered activated carbon on the filtration effect of 48%vol strong-flavor (Nongxiangxing) Baijiu was systematically compared.
XUE Runping, XIE Zhengmin, ZHENG Jia, ZHAO Dong, LI Maochun, HUANG Jian, YE Huaxia, ZHANG Qian, WANG Xingming
doaj   +1 more source

Does the instability of economic development affect the elasticity of the labour market?

Review of Economic Perspectives, 2021
Despite extensive research, the estimates of changes in employment are heterogeneous in different conditions of economic development. In this study, we examined the impact of the instability of economic growth on the elasticity of the labour market in a ...
Daňová Monika, Vozárová Ivana Kravčáková   +1 more
doaj   +1 more source

Early Functional Treatment and Modern Cast Making for Indications in Hand Surgery

Advances in Orthopedics, 2016
Cast treatment can serve both as a nonsurgical treatment option and as a means for providing postoperative protection. However, with the duration of immobilization intervals, the benefits of cast treatment, especially in hand surgery, are at risk of ...
S. Bohr, N. Pallua
doaj   +1 more source