Results 71 to 80 of about 122,905 (293)

TargetGen‐RNN model discovers novel antibiotic compound targeting drug‐resistant Staphylococcus aureus

open access: yesInterdisciplinary Medicine, EarlyView.
TargetGen‐recurrent neural network (RNN), an advanced generative model, generated 28,708 unique and novel compounds, identifying SAK‐2970 as a potent antibiotic against drug‐resistant Staphylococcus aureus. Exhibiting strong biofilm inhibition, high therapeutic efficacy, and minimal systemic toxicity in vivo, SAK‐2970 highlights its safety and clinical
Shakeel Ahmad Khan   +2 more
wiley   +1 more source

Which transport modes do people use to travel to coworking spaces (CWSs)?

open access: yesMultimodal Transportation, 2023
: There are many different ways of practicing coworking, and many different forms of CoWorking Spaces (CWSs). In this paper, we define CWSs in economic and spatial terms, and we provide some explanations on the transport mode used to travel to.
Stéphanie Souche-Le Corvec
doaj   +1 more source

Energy Justice in Transition: Perceptions From India's Coal‐Dependent Regions

open access: yesInternational Studies of Economics, EarlyView.
ABSTRACT Climate change has emerged as a critical barrier to economic development, prompting a global shift toward low‐carbon energy systems. For India, whose economy remains heavily reliant on coal, this transition entails complex socioeconomic and institutional challenges related to energy security, livelihoods, and regional dependence.
Srishti Minocha   +2 more
wiley   +1 more source

Analysis of Cross-Border Regional Homogeneity and Its Effects on Regional Resilience and Competitiveness

open access: yesActa Universitatis Sapientiae: Economics and Business, 2017
The resilience of a region may affect how it reacts to economic crises and exogenous shocks. In a complex study, it is not sufficient merely to have knowledge of all the macro-indices of the regions, but it is also necessary to study internal micro ...
Fazekas Nikolett   +2 more
doaj   +1 more source

Can We Detect the Anisotropic Shapes of Quasar HII Regions During Reionization Through The Small-Scale Redshifted 21cm Power Spectrum?

open access: yes, 2007
Light travel time delays distort the apparent shapes of HII regions surrounding bright quasars during early stages of cosmic reionization. Individual HII regions may remain undetectable in forthcoming redshifted 21 cm experiments. However, the systematic
Alvarez M. A.   +5 more
core   +1 more source

A method of implementing Hartree-Fock calculations with zero- and finite-range interactions [PDF]

open access: yes, 2001
We develop a new method of implementing the Hartree-Fock calculations. A class of Gaussian bases is assumed, which includes the Kamimura-Gauss basis-set as well as the set equivalent to the harmonic-oscillator basis-set.
Andō   +26 more
core   +2 more sources

Integrative Genomics Reveals Causal Pleiotropy and Therapeutic Opportunities at the Interface of Acute Pancreatitis and Infection

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Understanding the genetic links between acute pancreatitis (AP) and its infectious comorbidities is crucial for prognosis and therapy, yet remains underexplored. Methods We conducted a comprehensive post‐GWAS analysis using large‐scale summary statistics for AP and 16 infectious diseases. To pinpoint pleiotropic genes, we integrated
Bo Zou   +6 more
wiley   +1 more source

Evaluation of the electron correlation for lithium atom (Li) in ground state

open access: yesمجلة بغداد للعلوم, 2009
The aim of this work is to study the correlation between the electrons for Li atom in ground state through the calculation of the inter-particle distribution function f (r12) and inter-particle expectation values .
Baghdad Science Journal
doaj   +1 more source

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling   +6 more
wiley   +1 more source

ANÁLISE EXPERIMENTAL DO HIDROCARBONETO R290 PARA A SUBSTITUIÇÃO DO CFC12 EM REFRIGERADOR DOMÉSTICO

open access: yesHolos, 2011
Recentemente, muita atenção tem sido dada aos chamados fluidos naturais, que são menos agressivos ao meio ambiente e também apresentam grande importância na necessidade latente do aumento da eficiência energética dos equipamentos em comparação aos ...
Jucelino Gomes da Silva   +1 more
doaj   +1 more source

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