Decreased response to acetylcholine during aging of aplysia neuron R15. [PDF]
PLoS ONE, 2013 How aging affects the communication between neurons is poorly understood. To address this question, we have studied the electrophysiological properties of identified neuron R15 of the marine mollusk Aplysia californica.
Komolitdin Akhmedov +6 more
doaj +5 more sources
ICG-r15 predicts esophageal varices in compensated liver cirrhosis: a noninvasive approach
BMC GastroenterologyObjective The aim of our study was to evaluate the indocyanine green (ICG) retention test as a noninvasive marker of esophageal varices(EV). Methods The clinical data of patients diagnosed with compensated liver cirrhosis in Tianjin Second People’s ...
Xu Han +6 more
doaj +4 more sources
Serotonin increases an anomalously rectifying K+ current in the Aplysia neuron R15. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1983 Previous work has shown that serotonin causes an increase in K+ conductance in the identified Aplysia neuron R15. This response is mediated by cAMP-dependent protein phosphorylation. The results presented here show that the K+ channel modulated by serotonin is an anomalous or inward rectifier (designated IR) that is present in R15 together with the ...
J A, Benson, I B, Levitan
exaly +4 more sources
Progress in Biophysics and Molecular Biology, 1985 Abstract We have concentrated our review on the single identified neurone R15 from the abdominal ganglion of aplysia . With the exception of the squid giant axon, R15 is probably the most widely studied cell in neurobiology. It has long attracted attention because of its bursting activity, its production of peptides, and its possible role in ...
W B, Adams, J A, Benson
exaly +4 more sources
FEBS Open Bio, 2021 Unfractionated heparin (UFH) is an anionic glycosaminoglycan that is widely used to prevent blood clotting. However, in certain cases, unwanted side effects can require it to be neutralized.
Tong Li +10 more
doaj +2 more sources
Use of liver stiffness measurement for liver resection surgery: correlation with indocyanine green clearance testing and post-operative outcome. [PDF]
PLoS ONE, 2013 BackgroundLiver stiffness measurement (LSM) using transient elastography has recently become available for the assessment of liver fibrosis. Whether LSM can predict the functional liver reserve in patients undergoing liver resection is not certain.AimTo ...
James Fung +10 more
doaj +3 more sources
Establishment of an in vivo analytical method for detecting total anti-UFH activity and pharmacokinetic study in PS and R15 in rats. [PDF]
PLoS ONEProtamine sulfate (PS), the only U.S. Food and Drug Administration (FDA)-approved heparin antagonist, is encumbered by several drawbacks. R15, a synthetic polyarginine peptide, has proven to be a promising protamine substitute in prior studies.
Huimin Li +6 more
doaj +2 more sources
Indocyanine Green Retention Rate at 15 Minutes as a Key Predictor of Clinically Significant Portal Hypertension in Cirrhosis: Development and Validation of a Superior Non-Invasive Diagnostic Model [PDF]
The Turkish Journal of GastroenterologyBackground/Aims: To assess the correlation between indocyanine green retention rate at 15 minutes (ICG-R15), liver stiffness mea surement (LSM), and other clinical indicators in cirrhotic patients, using hepatic venous pressure gradient (HVPG) as a ...
Han Hu +4 more
doaj +2 more sources
ICG clearance as an indicator of augmented hepatic clearance and subtherapeutic drug concentrations in septic patients [PDF]
BMC AnesthesiologyPurpose To assess indocyanine green (ICG) clearance as a quantitative indicator of augmented hepatic clearance (AHC) in septic patients and to evaluate its impact on subtherapeutic antibiotic concentrations and 28-day mortality.
Ying Xu +6 more
doaj +2 more sources
BMC Medical Imaging, 2023 Objective The indocyanine green retention rate at 15 min (ICG-R15) is a useful tool to evaluate the functional liver reserve before hepatectomy for liver cancer.
Ling Zhu +7 more
doaj +1 more source