Results 101 to 110 of about 1,675,649 (296)

ExtFig7B_SLC7A5_intron_R1-R2-R3_LG290-292-293_annotated.tif

open access: yes, 2023
Xrn1 knock out A549 cells were infected with WT A/Puerto Rico/8/1984 (H1N1) ("PR8"), or PA-X deficient PR8-PA(∆X) viruses, or mock infected for 16 hours before RNA extraction. 5’RACE was then performed using primers specific for BCAP31 or SLC7A5 that can
Marta Gaglia (14243924)
core   +1 more source

A case study of Usher’s syndrome [PDF]

open access: yesPerspectives In Medical Research, 2018
Usher’s syndrome is the most common condition that affects both hearing and vision. The major symptoms of Usher’s syndrome are hearing loss and an eye disorder called retinitis pigmentosa, or RP.
Kapil S1 , Arvind R2
doaj  

A two-stage R2 indicator based evolutionary algorithm for many-objective optimization

open access: yesApplied Soft Computing, 2018
R2 indicator based multi-objective evolutionary algorithms (R2-MOEAs) have achieved promising performance on traditional multi-objective optimization problems (MOPs) with two and three objectives, but still cannot well handle many-objective optimization ...
Fei Li   +3 more
semanticscholar   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

EXPOSE-R2: The Astrobiological ESA Mission on Board of the International Space Station

open access: yesFrontiers in Microbiology, 2017
On July 23, 2014, the Progress cargo spacecraft 56P was launched from Baikonur to the International Space Station (ISS), carrying EXPOSE-R2, the third ESA (European Space Agency) EXPOSE facility, the second EXPOSE on the outside platform of the Russian ...
E. Rabbow   +9 more
semanticscholar   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

A study of the smooth muscle relaxant actions of harman alkaloids isolated from the seeds of peganum harmala [PDF]

open access: yesPerspectives In Medical Research, 2018
Introduction: The plant Peganum harmala is a shrub native to the arid parts of the world including India. It’s therapeutic value is attributed to the presence of alkaloids harmala and harmine in the dried ripe seeds.
Rajkumar T1 , Devde R2
doaj  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

PREPARATION OF METAL-SULFUR-CLUSTERS BY SIMPLE REACTION OF METAL-SALTS WITH H2S - R2(NH4)[CU3S12], R2[CU4S12] CH3CN, R2[CU4S12.8], R2[FE2S2(S5)2], R2[FES4BR4], R2[FE4S4BR2CL2], R2[FE4S4CL4], R2[FE2S2CL4] (R=PPH4) AND [FE(DMF)6][FE2S2CL4]

open access: yes, 1989
Müller A, Schladerbeck NH, Krickemeyer E, et al. Darstellung von Metall-Schwefel-Clustern durch einfache Reaktion von Metallsalzen mit H2S - R2(NH4)[CU3S12], R2[CU4S12] CH3CN, R2[CU4S12.8], R2[FE2S2(S5)2], R2[FES4BR4], R2[FE4S4BR2CL2], R2[FE4S4CL4], R2 ...
Krickemeyer, Erich   +6 more
core   +1 more source

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