Results 1 to 10 of about 244,701 (198)

Subcutaneous administration of the malaria R21/Matrix M vaccine and immune complex formation with anti-circumsporozoite protein mAb 2A10 elicit protective efficacy in mice [PDF]

Frontiers in Immunology
IntroductionR21, the most efficacious malaria vaccine to date, has been recommended by the World Health Organization (WHO) for the prevention of malaria in children. The current vaccination schedule requires three intramuscular doses per year. Optimizing
Ekta Mukhopadhyay, César López Camacho, Adrian V. S. Hill, Ahmed M. Salman   +3 more
doaj   +4 more sources

Seasonal mass vaccination with R21/Matrix-M for malaria elimination (SERVAL): protocol of the cluster randomised trial [PDF]

Trials
Introduction Progress in malaria control has stalled since 2015, highlighting the need for new control tools. The R21/Matrix-M (R21) malaria vaccine, a pre-erythrocytic vaccine recently approved by WHO for small children, may be one of these tools.
Edgard D. Dabira, H. Magloire Natama, Fatou Jaiteh, Koen Peeters Grietens, Fadima Y. Bocoum, Mamadou Ousmane Ndiath, Nuredin Mohammed, Balla Gibba, Adrian V S Hill, Azra Ghani, Annette Erhart, Halidou Tinto, Umberto D’Alessandro   +12 more
doaj   +5 more sources

Awareness, acceptability, and willingness to pay for the R21/Matrix-M malaria vaccine: a cross-sectional study among pregnant women and nursing mothers in Enugu State, Nigeria [PDF]

BMC Public Health
Background The R21/Matrix-M vaccine has significantly reduced incident malaria in children aged 3–36 months, but awareness, acceptance, and affordability of the vaccine are key to its successful rollout.
Obinna Felix Dim, Uzochukwu Emmanuel Chima, Francis Chibuike Iloabuchi, Chigozie Gloria Anene-Okeke, Chukwuemeka Augustine Nwachuya, Jennifer Chinaecherem Onyehalu, Anthony Uche Umeh, Chinonso Anne Agbo, Juliet Ekenedilichukwu Agbo, Abdulmuminu Isah   +9 more
doaj   +4 more sources

R21/Matrix-M malaria vaccine drives diverse immune responses in pre-exposed adults: insights from a phase IIb controlled human malaria infection trial [PDF]

Frontiers in Immunology
IntroductionThe recently licenced R21/Matrix-M vaccine induces a protective antibody response. In this study, we examined vaccine-induced responses in semi-immune adults in a controlled human malaria infection (CHMI) Phase IIb clinical trial ...
Elizabeth Kibwana, Caroline Bundi, Domtila Kimani, Lydia Nyamako, Kelvias Keter, Agnes Mutiso, Rodney Ogwang, Duncan Bellamy, Katerina Rapi, Amelia Bajer, Samuel Provstgaard-Morys, Lisa Stockdale, Olivia Munoz, Mehreen S. Datoo, Alison Lawrie, Fernando Ramos-Lopez, Rachel Roberts, Mainga Hamaluba, Mainga Hamaluba, Adrian V. S. Hill, Philip Bejon, Philip Bejon, Katie J. Ewer, Melissa Kapulu, Melissa Kapulu   +24 more
doaj   +4 more sources

Acceptability of the R21/Matrix-M malaria vaccine alongside existing malaria interventions in the trial context [PDF]

BMJ Global Health
Background The R21/Matrix-M malaria vaccine has been shown to provide high protective efficacy against malaria in a phase III trial, and has been recommended for use by WHO. The vaccine will soon be deployed at scale in sub-Saharan Africa.
Jayne Webster, Brian Greenwood, Daniel Chandramohan, Alassane Dicko, Issaka Sagara, Djibrilla Issiaka, Adrian VS Hill, Halimatou Diawara, Fatoumata Koita, Seydou Traoré, Jane Grant, Mehreen Datoo, Mala Sylla, Abdrahmane Boncane Dicko   +13 more
doaj   +2 more sources

Systematic Development and Validation of a Bradford-Based Protein Quantification Method for Novel Multi-Dose R21 Malaria Vaccine Formulated with 2-Phenoxy Ethanol (2-PE). [PDF]

Vaccines (Basel)
Jena R, Ranade D, Chaudhari P, Salunke A, Mahamuni A, Gairola S.   +5 more
europepmc   +3 more sources

B and T cell responses to pre-erythrocytic R21/Matrix-M and blood-stage RH5.1/Matrix-M malaria vaccines in endemic settings [PDF]

Bundi CK, Muñoz O, Kibwana E, Bellamy D, Stockdale L, Barrett JR, McHugh K, Mtaka I, Kalinga W, Kimani D, Nyamako L, Keter K, Ogwang R, Hill AV, Bejon P, Hamaluba M, Silk SE, Minassian AM, Draper SJ, Olotu AI, Kapulu M, Ewer KJ, Nielsen CM.   +22 more
europepmc   +2 more sources

Physicians' knowledge of, and willingness to encourage caregivers to partake in the RTS S/AS01 and R21 matrix M malaria vaccines roll out - a national survey in Nigeria. [PDF]

BMC Infect Dis
Oboh MA, Adeleke OT, Adeleke OV, Awotunde TA.   +3 more
europepmc   +3 more sources

Psychological correlates of eating behavior in overweight/obese adolescents in Taiwan: Psychometric and correlation analysis of the Three-Factor Eating Questionnaire (TFEQ)-R21

Pediatrics and Neonatology, 2021
Background: The Three-Factor Eating Questionnaire (TFEQ) is a self-assessment scale used widely in the studies of eating behavior, but its short form TFEQ-R21 has not been validated in the Taiwanese population.
Yu-Wen Lin, Chung-Ying Lin, Carol Strong, Chih-Hsiang Liu, Yi-Ping Hsieh, Yi-Ching Lin, Meng-Che Tsai   +6 more
doaj   +1 more source

The Application of the Simplified Speculative Frame Method for Monitoring the Development of the Housing Market

Real Estate Management and Valuation, 2022
This article contributes to research into price dynamics on the real estate market. It proposes a simplified index-based speculative frame method for measuring above-average increases and decreases in real estate prices and monitoring market performance.
Brzezicka Justyna
doaj   +1 more source