Results 1 to 10 of about 3,872 (187)
A Novel RANKL/RANK Inhibitor IMB-R38 Inhibits Osteoporosis Through Regulating Bone Metabolism [PDF]
International Journal of Molecular SciencesOsteoporosis is a systemic skeletal disease that severely impairs the health of the elderly population. The interaction between the receptor activator of the NF-κB ligand (RANKL) and its receptor RANK is critical for osteoclast differentiation and function. Therefore, targeting the RANKL/RANK interaction represents a promising strategy for osteoporosis.
Zhang Y +13 more
exaly +6 more sources
The Disaster to the Airship R38 [PDF]
Nature, 1921 IN the article on “The Disaster to the Airship R38” in NATURE of September 1, the author laments that, in consequence of it, airship development is to be abandoned by our, Government, and airship design is referred to as being a matter of experience and guessing.
exaly +9 more sources
Retinoic acid therapy resistance progresses from unilineage to bilineage in HL-60 leukemic blasts. [PDF]
PLoS ONE, 2014 Emergent resistance can be progressive and driven by global signaling aberrations. All-trans retinoic acid (RA) is the standard therapeutic agent for acute promyelocytic leukemia, but 10-20% of patients are not responsive, and initially responsive ...
Holly A Jensen +5 more
doaj +2 more sources
R38. Guillelmus de Parisiis Op?, † inter 1311–1314, Guillelmus Baufeti?,† 1320 [PDF]
, 2007 This chapter presents the dialogue between the Peter and the Print Gilo, G. or Guil on the seven Sacraments. It gives title, incipit and explicit as well as information on author, date, textual transmission, editions and a summary of the contents. The first sentences of the Guil make relationship between the Peter and the Guil: Peter has been ordained ...
exaly +5 more sources
Characterization of Endophytic Diazotroph Bacteria Isolated from Rice
Hayati Journal of Biosciences, 2010 Attempt to extend the biological nitrogen fixation to important crops such as rice has been conducted by isolating endophytic diazotrophs from rice rhizosphere and roots. In this study, three bacterial isolates of R2, R4, and E4 isolated from rice-legume
JOKO PRAYITNO, BARRY ROLFE
doaj +3 more sources
Involvement of the N Domain Residues E34, K35, and R38 in the Functionally Active Structure of Escherichia coli Lon Protease [PDF]
Acta Naturae, 2020 ATP-dependent Lon protease of Escherichia coli (EcLon), which belongs to the superfamily of AAA+ proteins, is a key component of the cellular proteome quality control system. It is responsible for the cleavage of mutant, damaged, and short-lived regulatory proteins that are potentially dangerous for the cell.
Andrianova, A. G. +5 more
openaire +2 more sources
ECONOMICS, 2023 Methodological approaches to assessing the level of innovation and investment attractiveness of the Western Ukrainian market of tourist services (WUMTS) substantiated the dependence of WUMTS on investment factors analyzed the level of competitiveness of ...
Pavlov Kostiantyn +4 more
doaj +1 more source
Oeconomia Copernicana, 2019 Research background: The economic benefits that arise with the development of airport infrastructure are accompanied by negative externalities. Legal, technical and institutional instruments are used to mitigate or limit these effects.
Iwona Foryś +2 more
doaj +1 more source
ECONOMICS, 2020 This article analyzes practices of attraction of foreign investments, studying their perspective of territorial competitiveness. The analysis of investment attraction practices is assessed for the impact on the territory, from a territorial enhancement ...
Celani Alberto +2 more
doaj +1 more source
Optimal city zoning and Big Data
Journal of Urban Management, 2022 The purpose of this paper is to characterize the optimal design of a residential zone in a linear town by a welfare-maximizing regulator when firms might know to some extent the position of the customers/citizens in the city.
Stefano Colombo
doaj +1 more source