Results 101 to 110 of about 2,227,188 (281)

New Results on Binary Codes Obtained by Doubling Construction

open access: yesCybernetics and Information Technologies, 2018
Binary codes created by doubling construction, including quasi-perfect ones with distance d = 4, are investigated. All [17·2r−6, 17·2r−6 − r, 4] quasi-perfect codes are classified.
Davydov Alexander A.   +2 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Application of the \(R\)-matrix method to determine the \((p,\gamma)\) cross-section

open access: yesCommunications in Physics
We apply the calculable \(R\)-matrix method to determine the \(p,\Gamma\) cross section. We compare our cross-section calculation for the benchmark \(^{12}\)C\((p,\gamma)^{13}\)N reaction with results from the widely used FRESCO and RADCAP codes, which ...
Hoang Phuc Nguyen
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Cyclic, LCD, and Self-Dual Codes over the Non-Frobenius Ring GR(p2,m)[u]/〈u2,pu

open access: yesMathematics
Let p be a prime number and m be a positive integer. In this paper, we investigate cyclic codes of length n over the local non-Frobenius ring R=GR(p2,m)[u], where u2=0 and pu=0.
Sami Alabiad, Alhanouf Ali Alhomaidhi
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Optimal Binary Locally Repairable Codes with Locality and Availability from Latin Squares

open access: yesMathematics
The rapid development of machine learning, large language models, and related technologies has greatly increased the demand for data storage capacity.
Nanyuan Cao   +3 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Construction of the cancer patients’ database based on the US National Health and Nutrition Examination Survey (NHANES) datasets for cancer epidemiology research

open access: yesBMC Medical Research Methodology
Background The US National Health and Nutrition Examination Survey (NHANES) dataset does not include a specific question or laboratory test to confirm a history of cancer diagnosis. However, if straightforward variables for cancer history are introduced,
Jinyoung Moon, Yongseok Mun
doaj   +1 more source

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