Results 91 to 100 of about 4,657,009 (295)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The role of technology monitoring to guide R&D programs: some Italian selected cases
, 2005 Technology monitoring may take on different meanings in a company’s day to day activities. In some cases it can be interpreted as a technology intelligence methodology, while in others it is understood as technology forecasting or even as technology ...
PETRONI G, NOSELLA, ANNA, SALANDRA R.
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Животновъдни науки, 2015 The aim of the present study was to analyze the correlation dependences between the quantitative indicators of phytoplankton and some environmental abiotic factors in Kardzhali and Dospat reservoirs for the period May 2009-April 2012.
КОСТАДИН ДОЧИН +3 more
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Analysis of virulence factors in cases of enterococcal endocarditis.
, 2004 Clin Microbiol Infect. 2004 Nov;10(11):1006-8. Analysis of virulence factors in cases of enterococcal endocarditis. Baldassarri L, Creti R, Arciola CR, Montanaro L, Venditti M, Di Rosa R.
Venditti M +5 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Internal and Firm-Specific Factors Affecting the Openness Degree: an Extensive Study in Italy
, 2010 Many companies claim they are adopting an open approach to innovation, but each of them with its own way. This paper explores the different models for opening up the innovation process adopted in practice, by means of an extended survey among Italian ...
MANZINI R +2 more
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Patient Preference and Adherence, 2010 Vassiliki Tsiantou1, Polina Pantzou2, Elpida Pavi1, George Koulierakis2, John Kyriopoulos11Department of Health Economics, National School of Public Health, Athens, Greece; 2Department of Sociology, National School of Public Health, Athens ...
Vassiliki Tsiantou +3 more
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