Results 111 to 120 of about 4,657,009 (295)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Advanced ScienceThe treatment of bone defects remains a substantial clinical challenge due to the lack of spatiotemporal management of the immune microenvironment, revascularization, and osteogenic differentiation.
Minhao Wu +9 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
R factors from Enterobacter group.
, 1978 Twenty-six R factors transmissible to E. coli K12 were derived from 79 strains of Enterobacter species isolated in various clinical specimens (urine, sputum, blood, pus); 71 of 79 strains were Enterobacter cloacae. Fifteen R factors were fi+: 14 belonged
E. Romero, M. Perduca, PAGANI, LAURA
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Resistência a isoniazida e rifampicina e história de tratamento anterior para tuberculose
Cadernos de Saúde PúblicaEm um estudo caso-controle, realizado no Rio de Janeiro, em 1994, foram incluídos 552 doentes de tuberculose com cultura positiva para Mycobacterium tuberculosis. A resistência a rifampicina e isoniazida foi de 1,8%. A variável de exposição foi "história
Sonia Natal +3 more
doaj
Innovation and R&D Policy: the Case of Transforming Sector and Business Services Sector
Management Letters/Cuadernos de Gestión, 2012 This paper analyzes some de factors that improve product innovation for the case of transformation sector and business services sector. Among this factors are human capital, technology, market competition, business expectations, and export intensity of ...
María Soledad Castaño Martínez
doaj
On r-factors with components containing specified vertices in a torus
AKCE International Journal of Graphs and CombinatoricsLet T be a graph obtained by taking the Cartesian product of n cycles of even lengths [Formula: see text]. It is known that for any subset of k vertices of T with [Formula: see text] there exists a 2-factor in T where each cycle contains exactly one of ...
A. V. Sonawane, Y. M. Borse
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source