Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast [PDF]
eLife, 2019 Production of healthy gametes in meiosis relies on the quality control and proper distribution of both nuclear and cytoplasmic contents. Meiotic differentiation naturally eliminates age-induced cellular damage by an unknown mechanism.
Grant A King +6 more
doaj +4 more sources
Extrachromosomal circular DNA are functional, heritable units that expand genomic plasticity and confer resilience [PDF]
Frontiers in Plant ScienceAlthough far less well-known and understood than chromosomal DNA, extrachromosomal circular DNA (eccDNA) are a pervasive and dynamic component of eukaryotic genomes.
Dana R. MacGregor, Christopher A. Saski
doaj +2 more sources
Extrachromosomal elements in a super-suppression system of yeast I. A nuclear gene controlling the inheritance of the extrachromosomal elements [PDF]
Heredity, 1971 Extrachromosomal elements in a super-suppression system of yeast I.
B S Cox
exaly +2 more sources
Structure of the Enterobacter pan-genome is revealed using machine learning [PDF]
Microbiology SpectrumThe growing availability of publicly accessible Enterobacter genomes offers an opportunity to reveal the structure of its pangenome, uncovering the catalog of genes across the genus and their distribution across the different species and subspecies of ...
Joshua T. Burrows +4 more
doaj +2 more sources
Connecting the dots: Epigenetic regulation of extrachromosomal and inherited DNA amplifications. [PDF]
J Biol ChemDNA amplification has intrigued scientists for decades. Since its discovery, significant progress has been made in understanding the mechanisms promoting DNA amplification and their associated function(s). While DNA copy gains were once thought to be regulated purely by stochastic processes, recent findings have revealed the important role of ...
Azadegan C, Santoro J, Whetstine JR.
europepmc +3 more sources
Type II and IV toxin-antitoxin systems coordinately stabilize the integrative and conjugative element of the ICESa2603 family conferring multiple drug resistance in Streptococcus suis. [PDF]
PLoS PathogensIntegrative and conjugative elements (ICEs) play a vital role in bacterial evolution by carrying essential genes that confer adaptive functions to the host.
Qibing Gu +6 more
doaj +2 more sources
Extrachromosomal inheritance of oligomycin resistance in yeast
FEBS Letters, 1970 Norio Gunge
exaly +3 more sources
Circlehunter: a tool to identify extrachromosomal circular DNA from ATAC-Seq data
Oncogenesis, 2023 In cancer, extrachromosomal circular DNA (ecDNA), or megabase-pair amplified circular DNA, plays an essential role in intercellular heterogeneity and tumor cell revolution because of its non-Mendelian inheritance.
Manqiu Yang +4 more
doaj +1 more source
PlasmidHostFinder: Prediction of Plasmid Hosts Using Random Forest
mSystems, 2022 Plasmids play a major role facilitating the spread of antimicrobial resistance between bacteria. Understanding the host range and dissemination trajectories of plasmids is critical for surveillance and prevention of antimicrobial resistance ...
Derya Aytan-Aktug +8 more
doaj +1 more source