Circlehunter: a tool to identify extrachromosomal circular DNA from ATAC-Seq data
Oncogenesis, 2023 In cancer, extrachromosomal circular DNA (ecDNA), or megabase-pair amplified circular DNA, plays an essential role in intercellular heterogeneity and tumor cell revolution because of its non-Mendelian inheritance.
Manqiu Yang +4 more
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PlasmidHostFinder: Prediction of Plasmid Hosts Using Random Forest
mSystems, 2022 Plasmids play a major role facilitating the spread of antimicrobial resistance between bacteria. Understanding the host range and dissemination trajectories of plasmids is critical for surveillance and prevention of antimicrobial resistance ...
Derya Aytan-Aktug +8 more
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EXPERIMENTAL ANALYSIS OF A PATERNALLY INHERITED EXTRACHROMOSOMAL FACTOR [PDF]
Genetics, 1986 ABSTRACT Virtually all known cases of extrachromosomal inheritance involve cytoplasmic inheritance through the maternal line. Recently, a paternally transmitted factor that causes the production of all-male families has been discovered in a parasitic wasp.
J H, Werren, J, van den Assem
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Identification and characterisation of an extrachromosomal element from a multidrug-resistant isolate of Trypanosoma brucei brucei [PDF]
, 1995 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Drug resistance together with difficulties involved in the development of new trypanocides are a major problem in the present control of African ...
Jamnadass, Harmanjeet Ramni
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Inheritance of extrachromosomal rDNA in Physarum polycephalum. [PDF]
Molecular and Cellular Biology, 1983 In the acellular slime mold Physarum polycephalum, the several hundred genes coding for rRNA are located on linear extrachromosomal DNA molecules of a discrete size, 60 kilobases. Each molecule contains two genes that are arranged in a palindromic fashion and separated by a central spacer region. We investigated how rDNA is inherited after meiosis. Two
P J, Ferris, V M, Vogt, C L, Truitt
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EcSeg: Semantic Segmentation of Metaphase Images Containing Extrachromosomal DNA
iScience, 2019 Summary: Oncogene amplification is one of the most common drivers of genetic events in cancer, potently promoting tumor development, growth, and progression.
Utkrisht Rajkumar +6 more
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Sperm-Mediated Transgenerational Inheritance
Frontiers in Microbiology, 2017 Spermatozoa of virtually all species can spontaneously take up exogenous DNA or RNA molecules and internalize them into nuclei. In this article I review evidence for a key role of a reverse transcriptase (RT) activity, encoded by LINE-1 retrotransposons,
Corrado Spadafora
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Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast
eLife, 2019 Production of healthy gametes in meiosis relies on the quality control and proper distribution of both nuclear and cytoplasmic contents. Meiotic differentiation naturally eliminates age-induced cellular damage by an unknown mechanism.
Grant A King +6 more
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An empirical study of evolution of inheritance in Java OSS [PDF]
, 2006 Previous studies of Object-Oriented (OO) software have reported avoidance of the inheritance mechanism and cast doubt on the wisdom of ‘deep’ inheritance levels.
Nasseri, E, Counsell, S, Shepperd, M J
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Reciprocal extrachromosomal inheritance in rye (Secale cereale L.) [PDF]
Hereditas, 2009 In an inbred line of Steel rye (Stalrag), a chlorophyll mutant (status paralbomaculatus) arose spontaneously that displayed both extrachromosomal maternal and paternal inheritance in crosses. Striata plants gave rise to albino, striata, and normal offspring when selfed.
SUNE FRÖST +2 more
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