Results 11 to 20 of about 208,533 (137)

Extrachromosomal elements in a super-suppression system of yeast I. A nuclear gene controlling the inheritance of the extrachromosomal elements [PDF]

Heredity, 1971
Extrachromosomal elements in a super-suppression system of yeast I.
B S Cox
exaly   +2 more sources

Reciprocal extrachromosomal inheritance in barley: the transmission of an infective element through male and female gametes

Suomen Maataloustieteellisen Seuran Tiedote
My backcross pollinations of 53 spontaneum barleys recurrently with cv. ‘Adorra’ resulted in a maternally inherited, partial spike fertility case assigned “58”.
H. Ahokas
semanticscholar   +3 more sources

Structure of the Enterobacter pan-genome is revealed using machine learning [PDF]

Microbiology Spectrum
The growing availability of publicly accessible Enterobacter genomes offers an opportunity to reveal the structure of its pangenome, uncovering the catalog of genes across the genus and their distribution across the different species and subspecies of ...
Joshua T. Burrows, Gaoyuan Li, Jonathan M. Monk, Siddharth M. Chauhan, Bernhard O. Palsson   +4 more
doaj   +2 more sources

Type II and IV toxin-antitoxin systems coordinately stabilize the integrative and conjugative element of the ICESa2603 family conferring multiple drug resistance in Streptococcus suis. [PDF]

PLoS Pathogens
Integrative and conjugative elements (ICEs) play a vital role in bacterial evolution by carrying essential genes that confer adaptive functions to the host.
Qibing Gu, Xiayu Zhu, Yong Yu, Tao Jiang, Zihao Pan, Jiale Ma, Huochun Yao   +6 more
doaj   +2 more sources

Connecting the dots: Epigenetic regulation of extrachromosomal and inherited DNA amplifications. [PDF]

J Biol Chem
DNA amplification has intrigued scientists for decades. Since its discovery, significant progress has been made in understanding the mechanisms promoting DNA amplification and their associated function(s). While DNA copy gains were once thought to be regulated purely by stochastic processes, recent findings have revealed the important role of ...
Azadegan C, Santoro J, Whetstine JR.
europepmc   +3 more sources

Aberrant inheritance of extrachromosomal DNA amplifications promotes cancer evolution

bioRxiv
Abstract Gene amplification in the form of extrachromosomal DNA (ecDNA) is a frequent driver in multiple cancer types. As ecDNA lack centromeres, their mitotic segregation does not follow traditional inheritance principles. However, the mechanisms that govern ecDNA fate following mitosis remain unclear.
Shir Marom, Inbar Lifshits Dayan, Venkata Narasimha Kadali, Mădălina Giurgiu-Kraljič, Gabriela Koifman, Karen Hakeny, Madhuri Chaurasia, Orléna Benamozig, R. Nevo, I. Azuri, Julia Ryvkin, R. Rotkopf, Gil Stelzer, Nino Oniashvili, Jacques Mardoukh, Sarah Pollock, Nika Iremadze, Z. Shipony, M. Kupervaser, N. Wigoda, Dena Leshkowitz, Z. Elazar, Esther R. Berko, A. Henssen, Ofer Shoshani   +24 more
semanticscholar   +2 more sources

What we learn from weed genetics. [PDF]

Am J Bot
American Journal of Botany, Volume 113, Issue 4, April 2026.
VanWallendael A.
europepmc   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles. [PDF]

FEBS Lett
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Casey D, Gao Z, Boyes J.
europepmc   +2 more sources

Extrachromosomal Circular DNA as a Cancer Biomarker: From Diagnosis to Treatment. [PDF]

Cancer Innov
Extrachromosomal circular DNA (eccDNA) is an emerging class of genetic material that exists outside the chromosomal genome. These circular DNA molecules are gaining increasing attention as important biomarkers in cancer research due to their roles in gene amplification, genetic heterogeneity, and drug resistance.
Li H, Cai J, Zhao G, Zou L.
europepmc   +2 more sources

Cancer: From a Genetic Disorder to a Systemic Disease. [PDF]

Adv Sci (Weinh)
Advanced Science, Volume 12, Issue 42, November 13, 2025.
Wong AH, Hu Y.
europepmc   +2 more sources