Results 11 to 20 of about 5,488 (166)

What we learn from weed genetics. [PDF]

open access: yesAm J Bot
American Journal of Botany, Volume 113, Issue 4, April 2026.
VanWallendael A.
europepmc   +2 more sources

Extrachromosomal Circular DNA as a Cancer Biomarker: From Diagnosis to Treatment. [PDF]

open access: yesCancer Innov
Extrachromosomal circular DNA (eccDNA) is an emerging class of genetic material that exists outside the chromosomal genome. These circular DNA molecules are gaining increasing attention as important biomarkers in cancer research due to their roles in gene amplification, genetic heterogeneity, and drug resistance.
Li H, Cai J, Zhao G, Zou L.
europepmc   +2 more sources

Cancer: From a Genetic Disorder to a Systemic Disease. [PDF]

open access: yesAdv Sci (Weinh)
Advanced Science, Volume 12, Issue 42, November 13, 2025.
Wong AH, Hu Y.
europepmc   +2 more sources

Research Advances of Extrachromosomal Circular DNA in Breast Cancer. [PDF]

open access: yesCancer Med
ABSTRACT Background This article presents an extensive review of the advancements in research concerning extrachromosomal circular DNA (ecDNA) within the context of breast cancer. As a distinct form of DNA, ecDNA is critically involved in the initiation, progression, diagnosis, and treatment of breast cancer.
Zhu X   +6 more
europepmc   +2 more sources

EXPERIMENTAL ANALYSIS OF A PATERNALLY INHERITED EXTRACHROMOSOMAL FACTOR [PDF]

open access: yesGenetics, 1986
ABSTRACT Virtually all known cases of extrachromosomal inheritance involve cytoplasmic inheritance through the maternal line. Recently, a paternally transmitted factor that causes the production of all-male families has been discovered in a parasitic wasp.
J H, Werren, J, van den Assem
openaire   +2 more sources

Inheritance of extrachromosomal rDNA in Physarum polycephalum. [PDF]

open access: yesMolecular and Cellular Biology, 1983
In the acellular slime mold Physarum polycephalum, the several hundred genes coding for rRNA are located on linear extrachromosomal DNA molecules of a discrete size, 60 kilobases. Each molecule contains two genes that are arranged in a palindromic fashion and separated by a central spacer region. We investigated how rDNA is inherited after meiosis. Two
P J, Ferris, V M, Vogt, C L, Truitt
openaire   +2 more sources

EcSeg: Semantic Segmentation of Metaphase Images Containing Extrachromosomal DNA

open access: yesiScience, 2019
Summary: Oncogene amplification is one of the most common drivers of genetic events in cancer, potently promoting tumor development, growth, and progression.
Utkrisht Rajkumar   +6 more
doaj   +1 more source

Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium. [PDF]

open access: yes, 2018
Adult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas and similar projects have provided a comprehensive understanding of the somatic alterations and ...
GLASS Consortium
core   +8 more sources

Sperm-Mediated Transgenerational Inheritance

open access: yesFrontiers in Microbiology, 2017
Spermatozoa of virtually all species can spontaneously take up exogenous DNA or RNA molecules and internalize them into nuclei. In this article I review evidence for a key role of a reverse transcriptase (RT) activity, encoded by LINE-1 retrotransposons,
Corrado Spadafora
doaj   +1 more source

An in vivo genetic screen for genes involved in spliced leader trans-splicing indicates a crucial role for continuous de novo spliced leader RNP assembly [PDF]

open access: yes, 2017
ACKNOWLEDGEMENTS Some strains were provided by the CGC, which is funded by NIH Office of Research Infrastructure Programs (P40 OD010440). We would also like to thank Prof.
Albrecht   +54 more
core   +1 more source

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