What we learn from weed genetics. [PDF]
American Journal of Botany, Volume 113, Issue 4, April 2026.
VanWallendael A.
europepmc +2 more sources
Extrachromosomal Circular DNA as a Cancer Biomarker: From Diagnosis to Treatment. [PDF]
Extrachromosomal circular DNA (eccDNA) is an emerging class of genetic material that exists outside the chromosomal genome. These circular DNA molecules are gaining increasing attention as important biomarkers in cancer research due to their roles in gene amplification, genetic heterogeneity, and drug resistance.
Li H, Cai J, Zhao G, Zou L.
europepmc +2 more sources
Cancer: From a Genetic Disorder to a Systemic Disease. [PDF]
Advanced Science, Volume 12, Issue 42, November 13, 2025.
Wong AH, Hu Y.
europepmc +2 more sources
Research Advances of Extrachromosomal Circular DNA in Breast Cancer. [PDF]
ABSTRACT Background This article presents an extensive review of the advancements in research concerning extrachromosomal circular DNA (ecDNA) within the context of breast cancer. As a distinct form of DNA, ecDNA is critically involved in the initiation, progression, diagnosis, and treatment of breast cancer.
Zhu X +6 more
europepmc +2 more sources
EXPERIMENTAL ANALYSIS OF A PATERNALLY INHERITED EXTRACHROMOSOMAL FACTOR [PDF]
ABSTRACT Virtually all known cases of extrachromosomal inheritance involve cytoplasmic inheritance through the maternal line. Recently, a paternally transmitted factor that causes the production of all-male families has been discovered in a parasitic wasp.
J H, Werren, J, van den Assem
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Inheritance of extrachromosomal rDNA in Physarum polycephalum. [PDF]
In the acellular slime mold Physarum polycephalum, the several hundred genes coding for rRNA are located on linear extrachromosomal DNA molecules of a discrete size, 60 kilobases. Each molecule contains two genes that are arranged in a palindromic fashion and separated by a central spacer region. We investigated how rDNA is inherited after meiosis. Two
P J, Ferris, V M, Vogt, C L, Truitt
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EcSeg: Semantic Segmentation of Metaphase Images Containing Extrachromosomal DNA
Summary: Oncogene amplification is one of the most common drivers of genetic events in cancer, potently promoting tumor development, growth, and progression.
Utkrisht Rajkumar +6 more
doaj +1 more source
Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium. [PDF]
Adult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas and similar projects have provided a comprehensive understanding of the somatic alterations and ...
GLASS Consortium
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Sperm-Mediated Transgenerational Inheritance
Spermatozoa of virtually all species can spontaneously take up exogenous DNA or RNA molecules and internalize them into nuclei. In this article I review evidence for a key role of a reverse transcriptase (RT) activity, encoded by LINE-1 retrotransposons,
Corrado Spadafora
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An in vivo genetic screen for genes involved in spliced leader trans-splicing indicates a crucial role for continuous de novo spliced leader RNP assembly [PDF]
ACKNOWLEDGEMENTS Some strains were provided by the CGC, which is funded by NIH Office of Research Infrastructure Programs (P40 OD010440). We would also like to thank Prof.
Albrecht +54 more
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