Results 151 to 160 of about 1,803,537 (266)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Workplace incivility and bullying across healthcare professionals: patterns and correlates - a cross-sectional study. [PDF]

BMJ Open
Yousefian S, Shayganfard M, Safari M, Javaheri J, Sadeghi B.   +4 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Ephedrine-Triggered Torsades de Pointes in Two Patients Following Desflurane-Induced QT Prolongation. [PDF]

J Arrhythm
Harada S, Kagawa Y, Okamoto R, Sakakura Y, Dohi K.   +4 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Prevalence and Correlates of Steatotic Liver Disease Among People With HIV in Uganda. [PDF]

Open Forum Infect Dis
Bibangambah P, Acan M, Ghoshhajra B, Erem G, Nassanga R, Ochieng A, Thondapu V, Lu MT, Randhawa M, Takigami A, Reynolds Z, Atwiine F, Tindimwebwa E, Gilbert RF, Hoepner SS, Passell E, Sagar S, Tong Y, Ntusi NAB, Hahn J, Gaziano T, Longenecker CT, Tsai AC, Manne-Goehler JM, Asiimwe S, Okello S, Siedner MJ.   +26 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Correction: Two-Year Outcomes for the Active and Healthy Families Pediatric Obesity Group Intervention for Families in an Emerging Latinx Community: a Mixed Methods Study. [PDF]

J Racial Ethn Health Disparities
La Charite J, DeCamp LR, Prichett L, Finney AG, Chen JY, Holler AE, Moon YJ, Mullins A, Ospino R, Porosnicu Rodriguez K, Polk S.   +10 more
europepmc   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

General practitioner residents' mental health and satisfaction during their vocational training. [PDF]

BMC Prim Care
Mohos A, Kolozsvári L, Rinfel J, Kiss-Kovács R, Torzsa P, Ágoston G.   +5 more
europepmc   +1 more source