Results 71 to 80 of about 1,049,465 (240)

The interplay between monocytes/macrophages and CD4+ T cell subsets in rheumatoid arthritis

Frontiers in Immunology, 2015
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by inflammation of the synovial lining (synovitis). The inflammation in the RA joint is associated with and driven by immune cell infiltration, synovial hyperproliferation and ...
Ceri A. Roberts, Abigail K. Dickinson, Leonie S. Taams   +2 more
doaj   +1 more source

Teerk Roo Ra Residencies [PDF]

, 2011
A series of works based on the Peel Island Residencies on Teerk Roo Ra in Moreton Bay during 2010/2011.\ud \ud This work was part of a larger research project, which was concerned with using animation to convey a sense of place. The primary investigation
Denaro, Chris
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Effects of Raloxifene (RAL) on proliferation in healthy (H) and rheumatoid arthritis (RA) synoviocytes

, 2011
Copyright information:Taken from "Raloxifene reduces urokinase-type plasminogen activator-dependent proliferation of synoviocytes from patients with rheumatoid arthritis"Arthritis Research & Therapy 2005;7(6):R1244-R1253.Published online 8 Sep 2005PMCID ...
R Livi (60646), A Rossi (60647), S Guiducci (60642), A Gabrielli (60648), N Iori (60650), G Fibbi (60651), M Cinelli (60644), F Perfetto (60645), M Del Rosso (60652), M Matucci Cerinic (60653), R Giacomelli (60649), A Del Rosso (60643)   +11 more
core   +1 more source

Self-reported adult footwear and the risks of lower limb osteoarthritis : the GOAL case control study [PDF]

, 2014
Background: Biomechanical factors may play a role in osteoarthritis (OA) development and progression. Previous biomechanical studies have indicated that types of footwear may modulate forces across the knee joint, and high heeled womens’ shoes in ...
Muthuri, Stella, Weiya Zhang, Zhang, W, Muthuri, S, Rose A Maciewicz, Maciewicz, Rose A., Muir, Kenneth, Doherty, M, Stella Muthuri, McWilliams, Daniel F., McWilliams, D F, Daniel F McWilliams, Muir, Kenneth R., Maciewicz, R A, Kenneth R Muir, Michael Doherty, Zhang, Weiya, Muir, K R; id_orcid, Doherty, Michael   +18 more
core   +2 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Understanding the Meaning of a Sentence and Text

Polylinguality and Transcultural Practices
Thanks to the concept of G.P. Melnikov, the technology of text’s meaning understanding is clarified. In simple cases of understanding in the linguistic consciousness of a person, a group of mental actors plays out a small drama of a sentence / utterance,
Evgeny F. Kirov
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

A20 Promoter rs5029924 Concomitant with rs2230926 and rs5029937 May Be a Prognostic Predictor for Joint Deformity or Refractory Rheumatoid Arthritis

International Journal of General Medicine
Lihua Zhu,1,* Lingling Zhou,2,3,* Liang Wang,4,* Cunte Chen,2 Jie Qiao,1 Xinran Huang,1 Xiaoyan Su,1 Shaohua Chen,2 Bo Li,2 Xiuli Wu,2 Yangqiu Li2 1Department of Rheumatology and Immunology, First Affiliated Hospital, Jinan University ...
Zhu L, Zhou L, Wang L, Chen C, Qiao J, Huang X, Su X, Chen S, Li B, Wu X, Li Y   +10 more
doaj  

Follicular Bronchiolitis in Rheumatoid Arthritis

The Journal of Association of Chest Physicians
Rheumatoid arthritis (RA) is a chronic inflammatory disorder with articular and extra-articular involvement. Pulmonary involvement is common in RA, mainly pleurisy, interstitial lung disease, pulmonary nodules, Caplan’s syndrome, and vasculitis ...
Neenu Najeeb, Vithal Chintalwar, Ketaki Utpat, Unnati Desai   +3 more
doaj   +1 more source