Results 81 to 90 of about 1,049,465 (240)

Aerolíneas Galápagos... ¡ra! ¡ra! ¡ra! [PDF]

open access: yes, 2002
Aerolíneas Galápagos... ¡RA! ¡RA! ¡RA!Las Aerolíneas Galápagos (AEROGAL) con el placer de todos los ecuatorianos que usamos el avión, anuncia con un equipo Boeing727-200 Advance, con matricula HC-CDJ, equipado con turbinas PyWJT8D-17; y con capacidad ...
Tobar Vega, Hugo
core  

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

PENGARUH KEGIATAN OUTBOUND TERHADAP MOTORIK KASAR ANAK DI KELOMPOK A RA AL-FATTAH BLOK SUKAMURNI DESA MAJA SELATAN KECAMATAN MAJA [PDF]

open access: yes, 2022
This research begins with the problem of underdeveloped gross motor skills in group A children, this is due to the ineffective use of strategies or learning methods as well as the delivery of learning that is less attractive to children, so children are ...
Aziizah, Sarah Aulia   +2 more
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Evaluation of “Tumor Necrosis Factor-Alpha for Rheumatoid Arthritis Patients” in Karbala Population

open access: yesMedical Journal of Babylon
Background: Rheumatoid arthritis (RA) refers to a persistent disease characterized by inflammation and gradual deterioration of the joints. Tumor necrosis factor-alpha (TNF-α) is a pro-inflammatory cytokine that plays a crucial role in controlling the ...
Roaa Noori Ali, Orass Madhi Shaheed
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Superoxide-producing lipoprotein fraction from Stevia leaves: definition of specific activity

open access: yesBMC Complementary and Alternative Medicine, 2019
Background Stevia rebaudiana Bertoni has various pharmacological actions, which includes antidiabetic, antioxidant, anti-inflammatory activities. The superoxide and consequently NADPH oxidase (Nox) are relevant targets involved in biological effects of ...
A. S. Isoyan   +6 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

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