Results 121 to 130 of about 8,118 (202)
Influence of RAAS Inhibition on Outflow Tract Obstruction in Hypertrophic Cardiomyopathy
Background: Two-thirds of patients with hypertrophic cardiomyopathy (HCM) develop symptomatic dynamic left ventricular outflow tract (LVOT) obstruction.
Julia Münch +2 more
core +1 more source
ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest +3 more
wiley +1 more source
Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates
ABSTRACT Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular‐kidney‐liver‐metabolic (CKLM) syndrome.
Virginia Anagnostopoulou +5 more
wiley +1 more source
ABSTRACT Aims While the new kidney protective therapies have transformed chronic kidney disease (CKD) management in patients with Type 2 diabetes mellitus (T2DM), treatment options for CKD in Type 1 diabetes mellitus (T1DM) have remained unchanged for 30 years, limited to renin–angiotensin system inhibitors (RASis).
Frances Perry +12 more
wiley +1 more source
Lines derived from spring bread wheat Omskaya 37 and possessing wheat-rye translocation 1RS.1BL have been studied and tested for resistance to fungal pathogens, drought, crop yield, and parameters characterizing ecological plasticity and stability. Three
I. A. Belan +7 more
doaj
ABSTRACT Translating local research into English as a lingua franca (ELF) connects local scholarship with global readership, but this process remains constrained by language barriers. Large language models (LLMs) offer advanced accessible solutions, but their responsible integration into academic translation requires a deeper understanding of the ...
Yueyue Huang, Yao Yao, Dechao Li
wiley +1 more source
Abstract Background Heart failure (HF) is a frequent cause of hospital admissions, carrying a high risk of hospital readmission and mortality. Alfred Health General Medicine Hospital in the Home (GM‐HITH) and Hospital Admission Risk Program (HARP) offer multidisciplinary HF care to multimorbid patients in bed‐substitution and non‐admitted community ...
Elana Forbes +8 more
wiley +1 more source
Among patients with type 2 diabetes undergoing percutaneous coronary intervention, thiazolidinedione use was independently associated with a significantly reduced risk of a composite of myocardial infarction, stroke, and all‐cause death, notably without an increased risk of admission for heart failure. ABSTRACT Background Thiazolidinediones (TZD) are a
Jinkwon Kim +5 more
wiley +1 more source
ABSTRACT Although there are conflicting clinical data on the efficacy of weight reduction in reducing secondary events in patients with comorbid overweight and obesity (OAO) and cardiovascular disease (CVD), there is excellent epidemiological and biological evidence of a cause–effect relationship between OAO, CVD, and other systemic complications ...
Wael Almahmeed +19 more
wiley +1 more source
Genetic associations of RAAS genes and chronic kidney disease: a systematic review and meta-analysis
Background Chronic kidney disease (CKD) and cardiovascular disease (CVD) are increasing public health burdens worldwide. The renin-angiotensin-aldosterone system (RAAS) regulates arterial blood pressure, extracellular volume, vascular resistance and ...
Smyth, Laura; id_orcid +3 more
core +1 more source

